About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Virus Kills Melanoma in Animal Model: Study

by Sheela Philomena on April 27, 2013 at 10:59 AM
Font : A-A+

 Virus Kills Melanoma in Animal Model: Study

Vesicular stomatitis virus (VSV) was found to kill human melanoma cells both in vitro and in animal models, says study.

"If it works as well in humans, this could confer a substantial benefit on patients afflicted with this deadly disease," says Anthony van den Pol, a researcher on the study. The research was published online ahead of print in the Journal of Virology.

Advertisement

Most normal cells resist virus infection by activating antiviral processes that protect nearby cells. "The working hypothesis was that since many cancer cells show a deficient ability to withstand virus infection, maybe a fast-acting virus such as VSV would be able to infect and kill cancer cells before the virus was eliminated by the immune system," says van den Pol. And indeed, the virus was able to selectively infect multiple deadly human melanomas that had been implanted in a mouse model, yet showed little infectivity towards normal mouse cells, he says.

Many different mechanisms are involved in innate immunity, the type of immunity that combats viral infection. van den Pol plans to investigate which specific mechanisms are malfunctioning in cancer cells, knowledge that would be hugely beneficial both in understanding how cancer affects immunity, and in enhancing a virus' ability to target cancer cells, he says.

Melanoma is the most deadly skin cancer. Most melanomas are incurable once they have metastasized into the body. The incidence of melanoma has tripled over the last three decades, and it accounts for approximately 75 percent of skin cancer-related deaths.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
First Dose of COVID-19 Vaccines May Improve Mental Health
Printed Temperature Sensors help with Continuous Temperature Monitoring
Health Benefits of Giloy
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Chicken Pox Skin Cancer Shigellosis Ultra-Violet Radiation Melanoma 

Recommended Reading
Melanoma
Melanoma is a dangerous form of skin cancer caused largely due to exposure to the sun's damaging UV ...
Study Links Skin Cancer to Future Risk of Other Cancers
White people who have non-melanoma skin cancer (types of skin cancer other than melanoma) be at ......
Transcription Factors Linked to Skin Cancer Melanoma: Research
At the University of North Carolina, researchers have discovered that transcription factors ......
English-Speaking Hispanics in US Take Fewer Protections Against Skin Cancer Than Spanish-Speaking Hispanics
English-speaking Hispanics in the US were found to be more likely to put themselves at a risk for .....
Chicken Pox
Chicken pox is an acute and highly contagious viral infection caused by the varicella zoster virus....
Shigellosis
Shigellosis or Bacillary Dysentery is a common cause of gastro-enteritis worldwide and can cause blo...
Skin Cancer
Skin cancer is an abnormal growth of skin cells. It can develop due to a continuous exposure to sun ...
Ultra-Violet Radiation
Ultraviolet radiations are electromagnetic radiations with wavelengths shorter than the shortest wav...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use