Brain damage, a potential post-operative complication following coronary artery bypass grafting (CABG) could be prevented by provision of xenon gas, a new study has found. The results of this first successful clinical trial can be found in Anesthesiology journal.
The researchers successfully administered xenon gas safely to a group of 12 patients undergoing CABG. This revolutionary technique could eventually pave way for development of new treatments for diseases associated with nerve damage such as stroke, spinal cord and brain injury.
Stem Cell Therapy In The Treatment Of Neurological Disorders
Stem Cell Therapy In The Treatment Of Neurological Disorders
Advertisement
Previous studies had established the effectiveness of xenon in neuroprotection. It inhibits the cascade of events that occur during stroke or brain/spinal cord injury. These events result in irreversible damage to the brain. Xenon, a neuroprotectant was found to inhibit activity of the glutamate receptor that resulted in nerve death. Prof. Nick Franks accidentally discovered this potential of xenon while he was involved in the identification of specific molecular targets related to anesthetic action.
Following demonstration of the feasibility of xenon administration to at risk individuals for development of brain damage, the researchers are keen about initiating a clinical trial to test the effectiveness of xenon in a large group of patients. Through current medical treatments, it is possible to prevent mortality associated with nerve damage; nothing can be done to inhibit nerve damage that causes long-term disability.
Xenon is a naturally occurring gas and no instances of toxicity has so far been reported, that makes it an ideal candidate for use as a neuroprotectant.
Xenon is a naturally occurring gas and no instances of toxicity has so far been reported, that makes it an ideal candidate for use as a neuroprotectant.
Chest Pain
Chest pain is a symptom that prompts an individual to seek emergency medical help. It may be due to a trivial problem or alternatively, due to a grave condition and not a diagnosis by itself.
Advertisement
Advertisement
|
Advertisement
Recommended Readings
Latest Mental Health News
The type of microglia appears to be key important for fine-tuning anxiety and obsessive compulsive disorder behaviors.
The study sheds light on the genetic architecture of bipolar disorder and provides more insights into the contribution of mosaic variants in human diseases.
People who live in disadvantaged neighbourhoods along with depressive symptoms tend to undergo premature aging.
There is an urgent need for mental health care in injured children after firearm injuries.
Recently, a noteworthy transformation has occurred, with 81 percent of workplaces now placing increased emphasis on employee mental health.