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Biomarkers May Indicate Alzheimer's Disease

by Medindia Content Team on Feb 6 2006 3:57 PM

The early signs of Alzheimer's disease can be identified by using the compounds, or biomarkers in the cerebrospinal fluid, according to scientific research conducted by Sweden’s Lund University. Loss of memory and confusion can also be interpreted as early signs of the onset of the disease, and it is not always easy to differentiate the symptoms of Alzheimer's, and that of growing old.

The condition has no known cure, but early detection and the administration of proper drugs can have a positive effect on the symptoms of the illness. The Alzheimer's disease gives rise to dementia among the elderly people. A total of 12 million people across the world are believed to be suffering from this condition. The chances of Alzheimer's setting in is greater in the case of old people with higher levels of tau and b-amyloid biomarkers in the cerebrospinal fluid, along with a mild cognitive impairment.

The fluids from 39 healthy volunteers and 137 people who suffer from a mild cognitive impairment were studied. After a period of between 4 years to 5 years, 15% were afflicted by dementia, while 42% developed Alzheimer's disease. Alzheimer's disease is indicated by abnormal concentrations of biomarkers. Alzheimer's disease can be detected at its early stages if the biomarkers were combined with cognitive tests, brain imaging and other clinical examinations.


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