About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

New findings, throw light on obesity

by Medindia Content Team on February 5, 2006 at 5:10 PM
Font : A-A+

New findings, throw light on obesity

An international team of researchers were studying Bardet-Biedl syndrome (BBS) and found that cells which lacks proper functional cilia gets lodged in the wrong places and cause obesity.

These cells which are in the brain which control appetite are at fault. These findings were published in the journal Nature Genetics. It was found that children born with BBS are obese and go blind and develop kidney failure.

Advertisement

Eight faulty genes are thought to be responsible for this disorder. Professor Peter Beales from University College London Institute of Child Health, working with colleagues from Canada, France and the US, has discovered that cilia play a very important role in this disorder.

In the mouse model of BBS, they found there were problems with tiny hair-like projections on cells, known as cilia. Without these hairs the cell cannot orient itself inside the body.
Advertisement

Hence researchers say that malfunction in the cilia could play a role in the symptoms of BBS and its related obesity. The researcher said that cilia on neurons on the brain in areas such as the hypothalamus which are involved in appetite control could be defective. He also said that BSS proteins present in the cilia are involved in a pathway known as planer cell polarity (PCP). It is this pathway which directs the cells to orient themselves in the embryo consequently on how the entire organism becomes arranged.

Further research is necessary to understand the different types of disorder that results due to defective cilial function.

Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
World Heart Day in 2022- Use Heart for Every Heart
Anemia among Indian Women and Children Remains a Cause of Concern- National Family Health Survey-5
H1N1 Influenza Prevention in Children: What Parents Need to Know
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Bariatric Surgery Obesity Bulimia Nervosa Liposuction 

Most Popular on Medindia

Color Blindness Calculator Drug Side Effects Calculator Diaphragmatic Hernia Nutam (400mg) (Piracetam) Noscaphene (Noscapine) Loram (2 mg) (Lorazepam) Hearing Loss Calculator The Essence of Yoga Pregnancy Confirmation Calculator Blood Donation - Recipients
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

New findings, throw light on obesity Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests