Laboratory Heart valve to study Heart diseases

Researcher Grande-Allen is developing a laboratory heart valve which could be used in testing the action of drugs on heart valves in an invitro model. This new bioreactor heart valve would help in breaking the etiology behind the cause of heart valve disease.

Research on the laboratory heart valve is funded with $750,000 from NIH and the researchers have found the difference in biochemical and alterations in heart valves between normal and heart disease humans and the researchers developed these laboratory valves with the help of using Pig valves and the researchers are planning to study the efficacy of new drugs developed for treating heart disease with the help of this laboratory heart valve and they are to test how the valves reacts to different biochemical alterations, their flexibility and texture modifications which would help to find new insights in heart disease research. Researchers have published the results of their initial study in Journal of the American College of Cardiology.