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Effect of cholesterol on health may be genetic

by Medindia Content Team on Jul 10 2005 1:26 PM

How the people’s body react to cholesterol increase depends on their genetic makeup, says a new study.

Bad cholesterol of low-density lipoprotein (LDL) may affect twins in the same way even if they live a lifestyle totally different from each other. Researchers of Department of Energy’s Lawrence Berkeley National Laboratory had looked into the health record of 28 pairs of identical twins, where one of them always had a more sedentary life than another.

The researchers had fond that there exists a correlation of 0.7 in responses tests of blood cholesterol levels regarding changes in diet among the siblings, although the responses varied in the total participants.

Researchers feel that irrespective of their lifestyles, if one of the twins had increased levels of LDL from a particular diet, then the other also had an increased level of LDL from the same diet. This shows the effect of genes in controlling the ill effects of blood cholesterol on health conditions. Some twins also seem to be more sensitive to changing levels of cholesterol than others.

Reference: American Journal of Clinical Nutrition, July 2005


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