Researchers studied 370 women between ages 18 to 45 and compared the effectiveness of a three-day regimen of amoxicillin-clavulanate to ciprofloxacin for treatment of acute uncomplicated cystitis.
Ciprofloxacin was found to be about 20-percent more effective than amoxicillin-clavulanate at producing a clinical cure resolution of the symptoms associated with UTI. Thus researchers say amoxicillin-clavulanate should be considered only when use of other first- and second-line antibiotics is not feasible.