Imagine having a decayed tooth repaired, painlessly, without drilling or shots of anesthesia to numb the area.
Wishful thinking? Not if two studies being conducted at the University at Buffalo's School of Dental Medicine show positive results.In one study, funded by a $100,000 grant by Apollonia, LLC, researchers in the school's Center for Dental Studies are testing a nasal spray that numbs the upper teeth.
"If this study is successful," said Sebastian Ciancio, D.D.S., principal investigator on the study, "it may mean the end of dental injections when dentists are performing procedures on the upper arch."
The second study, set to begin in coming months, will test the use of ozone to kill bacteria in a decayed tooth and its potential to eliminate the need for the dreaded drill, at least to repair simple cavities. Researchers at UB and two other U.S. dental schools will conduct the research, which is funded by a $1.5 million grant from Curozone, Inc. and Kavo Dental Manufacturing Co. UB's portion is $400,000.
Ciancio, who also is the UB principal investigator on this study, said the ozone delivery device currently is being used in Europe. "If the U.S. studies are successful, it should be available in this country in about two years," he said.
The nasal spray study is testing the effectiveness in dental procedures of a topical anesthetic normally used by ear, nose and throat physicians when they operate on the nose. Patients who received this anesthetic for that purpose reported it also numbed their upper teeth, sparking interest in using it for dental procedures.
Advertisement
Co-investigators, all from the UB dental school, are Eugene Pantera, D.D.S., Sandra Shostad, D.D.S., and Joseph Bonavilla, D.D.S.
Advertisement
"Following application of the ozone, patients will use a remineralizing solution, which strengthens the weakened tooth structure and, in many cases, eliminates the need for any dental drilling," said Ciancio.
Additional investigators on this study are Othman Shibly, D.D.S., Jude Fabiano, D.D.S., Benita Sobieroj, D.D.S., Maureen Donley, D.D.S., and Nina Kim, D.D.S., all from the UB dental school faculty.
Source-Bio-Bio Technology
SRI