About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Marijuana Holds Promise for Alzheimer’s Sufferers

by Medindia Content Team on October 10, 2006 at 3:43 AM
Font : A-A+

Marijuana Holds Promise for Alzheimer’s Sufferers

A key component, THC in marijuana may soon be used in a new generation of drugs to protect the brain form the ravages of Alzheimer's disease according to a new study.

Lab studies by researchers from the Scripps Research Institute, showed that THC blocked enzymes that lead to the formation of Alzheimer's plaques in sufferers' brains more current Alzheimer's drugs.

Advertisement

Alzheimer's disease has been found to be the leading cause of dementia among the elderly with about 290,000 Canadians over 65 affected by the disease. The Alzheimer Society of Canada has estimated a doubling of the number of cases over the next two decades with most of the victims being women. Till date no cure has been found for this progressive, degenerative brain disease.

Kim Janda, director of the Worm Institute of Research and Medicine at the institute, said the findings offer "evidence that THC possesses remarkable inhibitory qualities."
Advertisement

"I'm not at all suggesting you smoke pot," said Janda who is working on the development of vaccines against cocaine, nicotine and substances of abuse.

The study authors wrote, "Our results provide a mechanism whereby the THC molecule can directly impact Alzheimer's disease pathology." They also predicted that THC would prove valuable as a model for developing new and more effective drugs to treat the disease.

This is one among the latest studies to suggest the compound that produces a high might also be protective to the brain. Marijuana-like compounds are already being tested in mice against the fatal brain disease ALS, or Lou Gehrig's disease.

People with Alzheimer's have been found to have low levels of acetylcholine, a brain chemical believed to be important for learning and memory.

Existing drugs help ease symptoms of the disease by blocking an enzyme that breaks down acetylcholine.

Janda's team found THC (delta-9-tetrahydrocannabinol) also did the same but at lower concentrations. In addition it also "blunted" the formation of fibrils, or long, thread-like fibers that get woven into healthy brain cells, eventually choking them.

The researchers believe they've found a way THC "can directly impact Alzheimer's disease pathology." Their work is published in Molecular Pharmaceutics.

Source: Medindia
NLA
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Monkeypox Outbreak: What it is, How Does it Spread & the Prevention
Seasonal Allergy Medications
How to Choose the Best Eczema-Friendly Moisturizer for Children?
View all
Recommended Reading
News Archive
Date
Category
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Cannabis Drug Abuse Drug Detox Marijuana 

Most Popular on Medindia

Find a Doctor Diaphragmatic Hernia Turmeric Powder - Health Benefits, Uses & Side Effects Blood - Sugar Chart Pregnancy Confirmation Calculator Indian Medical Journals How to Reduce School Bag Weight - Simple Tips Blood Donation - Recipients Iron Intake Calculator Hearing Loss Calculator

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
ASK A DOCTOR ONLINE