RTI International Distinguished Fellow and Director of the Center for Organic and Medicinal Chemistry F. Ivy Carroll, Ph.D., has been presented the College on Problems of Drug Dependence's 2006 Nathan B. Eddy Memorial Award for outstanding research in the field of drug addiction.
Carroll has led RTI research focusing on substance abuse treatments for more than 30 years. Among his many achievements, Carroll developed RTI-336 and JDTic, two pharmacotherapies for the treatment of cocaine abuse and the prevention of relapse to cocaine use that are planned for clinical studies next year.
Earlier research led to the development of Iodine-123 RTI-55, which serves as a diagnostic agent for Parkinson's disease as well as a clinical tool to study drug abuse patients. Carroll's work also resulted in the identification of compounds with the potential to treat depression and other neurological disorders.
Carroll has written 383 peer-reviewed articles and 30 book chapters and has completed 34 patents and patent applications in the fields of organic synthesis, medicinal chemistry, biochemistry and drug abuse research.
In addition to the Eddy Award, the National Institute on Drug Abuse awarded Carroll the Pacesetter Award in 1993 and the MERIT Award in 1996 for his research on the biochemical mechanisms of the action of cocaine. Carroll also earned the Distinguished Lecturer Award from the North Carolina Section of the American Chemical Society in 1993, the Southern Chemist Award in 2000, the Herty Award and the RTI Margaret E. Knox Excellence Award in 2001, and the American Chemical Society Medicinal Chemistry Award in 2002. He also was selected as Fellow of the American Association of Pharmaceutical Scientists and the American Association for the Advancement of Science.
"Ivy Carroll is truly an expert in drug addiction research and a deserving recipient of this award," said Satinder Sethi, Ph.D., executive vice president of RTI's Science and Engineering Group. "Ivy's dedication to help those suffering from addiction has contributed significantly to this field of research and reflects RTI's mission and commitment to improve the human condition."