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Study Suggests Links Between Diabetes And Multiple Sclerosis

by Medindia Content Team on July 15, 2006 at 12:44 PM
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Study Suggests Links Between Diabetes And Multiple Sclerosis

People with type-1 diabetes are more prone to develop multiple sclerosis (MS) in comparison to non-diabetic people, a Denmark study reveals.

Both type-1 diabetes and MS are auto-immune diseases, where the body builds up an aberrant immune response against itself, attacking insulin-producing cells in patients with diabetes, and the myelin sheath of the neurons in those suffering from MS.

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Dr. Nete M. Nielsen, from the Statens Serum Institut in Copenhagen, and colleagues, evaluated the emergence of MS in 6078 patients with type-1 diabetes with more than a decade of follow-up, and observed that patients with type- 1 diabetes had a more than three-fold increased risk of MS.

Their study has been reported in the Archives of Neurology.

The researchers also studied the presence of type-1 diabetes in 14,771 first-degree relatives of 11,862 MS patients and found that first-degree relatives of MS patients had a 63 percent increased risk of developing type-1 diabetes.
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"To our knowledge, the present study is the first truly nationwide cohort study to demonstrate intra -individual and, to a lesser degree, intra -familial co-occurrence of MS and type 1 diabetes," the investigators claim.

"The underlying mechanisms remain unknown, but may involve both genetic and environmental factors." they added.

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