About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Valtrex Prevents the Need for C-Section among Women Infected With Genital Herpes

by Medindia Content Team on July 11, 2006 at 10:24 AM
Font : A-A+

Valtrex Prevents the Need for C-Section among Women Infected With Genital Herpes

Researchers from the University of Texas, Southwestern Medical Center have found a new anti viral drug which prevents the necessity of a caesarean section in pregnant woman who have a history of genital herpes.

The UT Southwestern study is the first large-scale confirmation that the drug valacyclovir hydrochloride (Valtrex) is effective in the last month of pregnancy, the researchers said.

Advertisement

The study appears in this month's issue of the journal Obstetrics and Gynecology. 'I think this will help immensely in giving doctors stronger evidence in using this treatment,' said Dr. Jeanne Sheffield, assistant professor of obstetrics and gynecology at UT Southwestern and lead author of the study. 'Besides reducing the number of herpes outbreaks at birth, we also dropped the numbers of women without symptoms who were shedding the virus into the birth canal.'

Herpes, one of the most common sexually transmitted viral infections, causes periods of genital sores, followed by months or years of dormancy. It can't be cured, although the number and severity of outbreaks can be reduced through medication. Many women of reproductive age are unaware that they have the virus. In rare cases, infants can catch herpes simplex virus from the birth canal or genital region of the mother during birth, even when the mother isn't showing symptoms. Current medical protocol is to offer C-sections to all women with active genital herpes lesions at the time of delivery.
Advertisement

Nonetheless, 70 percent of neonatal herpes cases occur in infants of women who asymptomatically shed the virus near delivery, according to the researchers. 'The whole goal of this study was to reduce active genital herpes lesions at delivery that require a Caesarean delivery to prevent neonatal herpes,' Dr. Sheffield said. The UT Southwestern study, which involved 338 pregnant women with a history of genital herpes, was a randomized, double-blind trial, with neither the doctors nor the women knowing who was getting the medication. Twenty-eight women had C-sections because of active herpes lesions.

Seven of the 170 women in the valacyclovir group, or 4 percent, had the operation, while 21 of the 168 women in the placebo group, or 13 percent, had C-sections. The 69 percent reduction in the rate of clinical herpes simplex virus at the time of delivery was statistically significant, the researchers said. None of the babies in either group were born with herpes. There also were no differences in complications between the valacyclovir and placebo groups. 'This work is a good example of a well-designed study that is of sufficient size to help clinicians and patients have confidence in the efficacy and safety of anti-viral suppression in late pregnancy,' said Dr. George Wendel, professor of obstetrics and gynecology and senior author of the study.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Vaccination  And Counter  Measures Against  Monkeypox
Indian Railways Special Concession on Health Grounds
COVID Toes
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Cesarean Section Genital Herpes 

Most Popular on Medindia

Nutam (400mg) (Piracetam) Pregnancy Confirmation Calculator Turmeric Powder - Health Benefits, Uses & Side Effects Iron Intake Calculator Drug Interaction Checker Blood - Sugar Chart Color Blindness Calculator Noscaphene (Noscapine) Diaphragmatic Hernia Indian Medical Journals

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use