About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Response to Diseases Vary at Gene Level

by Medindia Content Team on July 8, 2006 at 11:51 AM
Font : A-A+

Response to Diseases Vary at Gene Level

Recent research has revealed that men and women often respond differently to diseases and drugs probably because of the differences in gene behavior in the organs of males and females.

Mice, which share 99 percent of their genes with humans, have been used as the subjects of the study of gene activity in its brain, fat, muscle and liver tissue. The results of the research have been published in August issue of the journal Genome Research.

Advertisement

According to Xia Yang, a postdoctoral fellow in cardiology at the University of California Los Angeles and lead researcher of this study "We previously had no good understanding of why the sexes vary in their relationship to different diseases".

"Our study discovered a genetic disparity that may explain why males and females diverge in terms of disease risk, rate and severity."

As study co-author Jake Lusis, a professor of human genetics at UCLA said although genes worked similarly in both sexes, there were striking and unexpected differences in the amount of gene expression between males and females. These findings could help to better understand diabetes, heart disease and obesity and thereby aid in gender-specific therapies.
Advertisement

It was found that in liver, fat and muscle tissue, the sex of the organism affected gene expression for several thousands of genes. However in the brain, the effect was limited to only some hundreds of genes.

Mainly genes involved in organ function, such as liver metabolism were found to be affected.

Luiss said that these differences could probably explain why studies have found ASA is better at preventing heart attack in men than women.

Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Prevent Hacking of Medical Devices: FDA Sounds Alarm
Black Water: Benefits and Uses
World Hypertension Day 2022 - Measure Blood Pressure Accurately, Control It, Live Longer!
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
DNA Finger Printing 

Most Popular on Medindia

Sanatogen Blood Donation - Recipients Drug Side Effects Calculator Iron Intake Calculator Selfie Addiction Calculator Find a Hospital Loram (2 mg) (Lorazepam) Nutam (400mg) (Piracetam) Turmeric Powder - Health Benefits, Uses & Side Effects Post-Nasal Drip

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use