"Clozapine is the last hope for many people. But there are long-term health implications. This study suggests that patients who need the most effective medication are between a rock and a hard place," said J. Steven Lamberti, the lead author of the study.
The study found that clozapine increased the risk of metabolic syndrome, a group of conditions that increase the risk for heart disease, stroke and diabetes.
The details of the study appear in latest issue of The American Journal of Psychiatry. The study said that the potential risks must be weighed with the benefits.