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Abnormal Heart Rhythm Controlled By Cholesterol Drugs

by Medindia Content Team on May 25, 2006 at 2:09 PM
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Abnormal Heart Rhythm Controlled By Cholesterol Drugs

cardiomyopathy,defibrillitor,Statins, a group of commonly used cholesterol-lowering drugs, used by patients with enlarged hearts (dilated cardiomyopathy) due to an anti-arrhythmic effect.

Scientists with the Multicenter defibrillators in Nonischemic Cardiomyopathy Treatment Evaluation (definite) committee evaluated about 458 sudden cardiac deaths with cardiomyopathy due to a survival benefit and effect of Statin therapy. Among these about, 229 patients were randomly selected to get an implantable Cardioverter defibrillator to treat their abnormal heart rhythm.

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However these devices are programmed to detect the abnormalities first, and to then deliver a shock to restore normal heart rhythm. On an average, 110 patients were found to take Statin, while 348 take drugs such as Lipitor, Pravachol and Zocor. Statin therapy pack a 78-percent reduced mortality rate for cardiac patients.

Dr. Jeffrey J. Goldberger of northwestern University in Chicago, reported a 39-percent lower mortality rate among patients who received a defibrillator and who were on statin therapy than other patients in a 2,000 days study.
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There was only 1 sudden death from arrhythmia among the patients who were receiving Statins, compared with 18 patients who were not on Statins and they require a shock to correct an abnormal heartbeat when compared to statin takers. Statins' benefits are may be due to their cholesterol-lowering effects, and primarily due to anti-inflammatory effects, antioxidant effects or effects on the nervous system.

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