About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Kidney Failure three times pronounced with obesity

by Medindia Content Team on May 12, 2006 at 5:16 PM
Font : A-A+

Kidney Failure three times pronounced with obesity

A study in the June Journal of the American Society of Nephrology has stated that obesity remains a high risk factor for chronic renal failure.

"Our results confirm an accumulating body of clinical and experimental data implicating obesity as an important causative factor in kidney disease," comments Dr. Elisabeth Ejerblad of Uppsala University, Sweden, lead author of the new study.

Advertisement

Dr. Ejerblad and colleagues assessed body mass index (BMI)—a measure of weight that considers the person's height—and other potential risk factors in 926 Swedish patients with moderately severe CRF. Chronic renal failure is gradual, irreversible loss of kidney function that can lead to end-stage renal disease (ESRD), a permanent loss of kidney function requiring dialysis or kidney transplantation. Nine hundred ninety-eight persons with normal kidney function were studied for comparison.

Obesity—defined as a BMI of 30 or higher—was a strong risk factor for CRF. Subjects who met the definition of obesity at any age were three to four times more likely to develop CRF. For women, morbid obesity—BMI 35 or higher—was also a risk factor for CRF.Risk was also increased for people who fell short of the study definition of obesity but were still overweight. Risk of CRF was tripled for both men and women who were overweight—BMI 25 or higher—at age 20 or later.
Advertisement

The link between obesity and CRF was strongest for diabetes-related kidney disease. However, for all subtypes, obesity doubled or tripled the risk of CRF. Even for people who had neither high blood pressure nor diabetes—both risk factors for kidney disease—being overweight at age 20 or older tripled the risk of CRF.

"Chronic renal failure is an escalating health problem throughout the world," says Dr. Ejerblad. "Because of the high rates of ESRD and death, it is of the utmost importance to identify potentially preventable causes or CRF." Rates of both obesity and CRF have risen rapidly in recent years but few studies have looked at the possible relationship between the two.

"Our study confirms an accumulating body of clinical and experimental data implicating obesity as a significant but preventable risk factor for chronic renal failure," Dr. Ejerblad adds. "Based on our findings, we estimate that obesity causes 15 percent of CRF in men and 11 percent in women. The excess risk for CRF among obese people appears mainly to be driven by a high prevalence of hypertension and/or type II diabetes, but additional pathways cannot be ruled out."

The article, entitled "Obesity and Risk of Chronic Renal Failure" will appear in print in the June issue of the Journal of the American Society of Nephrology.

Source: Newswise
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Fermented Skin Care
Television Binge-Watching May Boost the Risk of Deadly Blood Clots
Western Diet may Augment the Risk of Autoimmune Diseases
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Bariatric Surgery Acute Renal Failure Glomerulonephritis Obesity Bulimia Nervosa Urinary Stones In Children Vesico-Ureteric Reflux Causing UTI in Children Hydronephrosis / Antenatal Counseling Kidney Disease Liposuction 
Recommended Reading
Acute Renal Failure
Acute renal failure is the sudden cessation of the functioning of kidneys, that can be due to reduce...
Bulimia Nervosa
The term ''Bulimia'' refers to episodes of uncontrolled excessive eating, known as "binges," followe...
Glomerulonephritis
Glomerulonephritis is used to describe several kidney disease that damage the glomeruli. Glomerulone...
Hydronephrosis / Antenatal Counseling
Currently most pregnant women undergo one or two ultrasound scans during their pregnancy....
Liposuction
Liposuction is a cosmetic procedure, which is used to suck out the excess or abnormal fat deposition...
Obesity
Obesity is a condition where there is excess accumulation of body fat which poses a risk to the heal...
Urinary Stones In Children
There is a wide misconception that only adults develop stones. On the contrary kidney stones are ver...
Vesico-Ureteric Reflux Causing UTI in Children
Bacterial infection of urinary bladder can cause pain and burning sensation while passing urine. Abn...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
ASK A DOCTOR ONLINE
I have read and I do accept terms of use - Telemedicine

Advantage Medindia: FREE subscription for 'Personalised Health & Wellness website with consultation' (Value Rs.300/-)