‘Identifying the strains which are more prone to causing infections in people will allow predicting a patient's disease outcome.’
Uri Sela, a clinical fellow in the laboratory of Vincent A. Fischetti, obtained these findings by analyzing blood samples from healthy volunteers whose immune cells had been challenged with different strains of Staphylococcus aureus
. In many other studies, however, scientists have drawn conclusions about the immune system's interactions with a bacterium based on experiments with a single strain, which may not be representative of the species as a whole, Sela says.
"Our findings are novel and unexpected," he notes, "and may set the stage for better ways to predict a patient's disease outcome and tailor treatment accordingly."