Vanillin in artificial vanilla extract could prevent or reduce psoriatic skin inflammation.
Psoriasis is an inflammatory skin disorder that affects about 125 million people worldwide, resulting in scaly red plaques that typically show up on the elbows, knees or scalp. Immune system proteins called interleukins (IL) 17 and 23 are known to be key players in the development of the condition.
Psoriasis
Psoriasis is a recurrent and complex inflammatory skin disorder that can have tremendous physical and psychological impact on the sufferer
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‘Vanillin reduces levels of pro-inflammatory markers that induce psoriasis and also the severity of skin inflammation.’
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Interestingly, vanillin can have effects on different interleukins that are involved in other inflammatory conditions and diseases. So, Chien-Yun Hsiang and Tin-Yun Ho wanted to see if treatment with vanillin could prevent psoriatic symptoms.
The researchers induced psoriatic skin inflammation on groups of mice by putting a compound called imiquimod on their skin. In addition, the mice were orally given daily doses (0, 1, 5, 10, 50 or 100 milligrams/kilograms of body weight) of vanillin for seven days. Mice treated with 50- or 100-milligram/kilograms of body weight doses had reduced psoriatic symptoms compared to those receiving smaller or no doses of vanillin.
In all mice treated with vanillin, IL-17 and IL-23 protein levels were decreased. The researchers say that vanillin was an effective compound against psoriatic skin inflammation in this animal model.
Source: Eurekalert
In all mice treated with vanillin, IL-17 and IL-23 protein levels were decreased. The researchers say that vanillin was an effective compound against psoriatic skin inflammation in this animal model.
Source: Eurekalert
Scalp Psoriasis
Scalp psoriasis, a common skin disorder causes lesions on the scalp. There is no cure for scalp psoriasis and can recur after treatment.
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 Nail PsoriasisPsoriasis is an autoimmune disease, which in rare cases can, also affect the nails, making them brittle, soft and painful. | Advertisement
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Diet for Psoriasis
Learn what causes psoriasis, the appropriate diet to follow and the importance of diet in the treatment of this medical condition.
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