About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER

Vaginal Estrogen Therapy Myths Debunked

by Rishika Gupta on December 30, 2018 at 8:14 PM
Font : A-A+

 Vaginal Estrogen Therapy Myths Debunked

Vaginal estrogen therapy was not associated with a higher risk of cardiovascular disease, cancer, or hip fractures as the myths suggested. This study followed women from the Nurses' Health Study for 18 years. The results of this study are published in the Menopause: The Journal of the North American Menopause Society.

Despite its proven effectiveness in treating the genital symptoms of menopause, low-dose vaginal estrogen therapy remains underused largely because of misperceptions regarding its safety. However, a new study that followed women from the Nurses' Health Study demonstrates that its use is not associated with a higher risk of cardiovascular disease or cancer. Results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).



Between 25% and 70% of postmenopausal women are affected by an array of genital and urinary issues collectively known as the genitourinary syndrome of menopause (GSM). Common symptoms include vaginal burning and irritation, a lack of lubrication, pain during intercourse, and urinary tract infections. Unlike hot flashes, which often accompany menopause, GSM symptoms do not resolve over time, are chronic, and can become progressively worse without treatment.

Low-dose vaginal estrogen therapy is the preferred and most effective treatment for GSM and is recommended by multiple professional societies, including NAMS, the American College of Obstetricians and Gynecologists, and the Endocrine Society. Multiple studies document the superior effectiveness of vaginal estrogen over nonhormone therapies and demonstrate that it provides better symptom relief than oral estrogen therapy.

As a result of misperceptions regarding its safety (which partially stem from the FDA-issued black-box warning that relates to systemic hormone therapy), vaginal estrogen therapy is not prescribed as often as it could be, leaving many postmenopausal women to experience a lower quality of life.

A new study that followed women from the Nurses' Health Study for more than 18 years, however, concluded that vaginal estrogen was not associated with a higher risk of cardiovascular disease, cancer, or hip fractures. This included risks for myocardial infarction, stroke, and pulmonary embolism, as well as breast, endometrial, ovarian, and colorectal cancers.

Study results appear in the article "Vaginal estrogen use and chronic disease risk in the Nurses' Health Study."

"Over-the-counter vaginal lubricants and moisturizers are often used as first-line treatments for women with symptoms of GSM," says Dr. JoAnn Pinkerton, NAMS executive director. "Persistent symptoms often need therapies such as local vaginal estrogen, intravaginal dehydroepiandrosterone, or oral ospemifene. This study adds to a growing body of data showing the long-term efficacy and safety of low-dose vaginal estrogen, which works primarily locally with minimal systemic absorption."

Source: Eurekalert

News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Link between Dietary Intake of Plant-based Essential Fatty Acids and Death Risk
Aspirin may be Harmful When Used for Preventing 1st Heart Attack, Stroke
Pregnancy Complications Elevated Among Symptomatic COVID-19 Women
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Oophorectomy Reiki and Pranic Healing Hormone Replacement Therapy Uterine Cancer Dealing with Menopause symptoms through lifestyle changes Everything You Need to Know about Vaginal Health Estrogen Dominance Hormonal Imbalance Perimenopause High Testosterone Level In Women / Hyperandrogenism 

Recommended Reading
Estrogens in Cows' Milk Do Not Pose Any Threat to Human Health
Estrogens found naturally in cows' milk are more likely to be safe for human consumption, reveals a ...
Age-related Increase in Estrogen Linked to Hernia
Increased estrogen level in mouse model weakens abdominal wall to cause hernia, stated new ......
New Options for Breast Cancer Drug Development Discovered in Estrogen Receptors
New study revealed a previously uncharacterized, bridge-like structure within the human estrogen ......
Estrogen Deficiency Could Lead to Anxiety and Memory Problems
Anxiety and memory problems increase as estrogen levels drop, found rat study....
Dealing with Menopause symptoms through lifestyle changes
You can deal with menopause symptoms such as hot flashes, weight gain and forgetfulness by making si...
Estrogen Dominance
Estrogen dominance is a condition with relatively high levels of estrogen and diminished progesteron...
Everything You Need to Know about Vaginal Health
How much do you know about vaginal health care? Find out everything you need to know about the most ...
High Testosterone Level In Women / Hyperandrogenism
High levels of testosterone in women, also known as hyperandrogenism is an endocrine disorder charac...
Hormonal Imbalance
Hormone imbalance - These signs and symptoms can be a red alert. Too much or too little of your body...
Hormone Replacement Therapy
Hormone Replacement Therapy can be likened to an ‘oasis in the desert’ for women in the throes of .....
Perimenopause
Perimenopause is a transition phase that lasts until menopause. The low estrogen levels during this ...
Uterine Cancer
Uterine Cancer or Cancer of the Uterus (or Endometrial Cancer) refer to cancers affecting the uterus...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use