Statin therapy has been recommended only for fewer people, including young adults with a higher risk of cardiovascular disease. The physicians may adhere to the U.S. Preventive Services Task Force (USPSTF) recommendations for statin therapy when compared with the 2013 American College of Cardiology/American Heart Association (ACC/AHA) guidelines, finds a study published in the journal JAMA. The 2013 ACC/AHA guidelines substantially expanded the population eligible for statin therapy by basing recommendations on an elevated 10-year risk of atherosclerotic cardiovascular disease (ASCVD). The 2016 USPSTF recommendations for primary prevention statin therapy increased the estimated ASCVD risk threshold for patients (including those with diabetes) and required the presence of at least one cardiovascular risk factor (i.e., hypertension, diabetes, dyslipidemia, or smoking) in addition to elevated risk. Michael J. Pencina, Ph.D., of Duke University, Durham, N.C., and colleagues used National Health and Nutrition Examination Survey (NHANES) data (2009-2014) to assess statin eligibility under the 2016 USPSTF recommendations vs the 2013 ACC/AHA cholesterol guidelines among a nationally representative sample of 3,416 U.S. adults ages 40 to 75 years with fasting lipid data and triglyceride levels of 400 mg/dl or less, without prior cardiovascular disease (CVD). ‘Statin therapy has been recommended for fewer people according to the U.S. Preventive Services Task Force (USPSTF) recommendations.’ The researchers found that if fully implemented, the USPSTF recommendations would be associated with statin initiation in 16 percent of adults without prior CVD, in addition to the 22 percent of adults already taking lipid-lowering therapy; in comparison, the ACC/AHA guidelines would be associated with statin initiation in an additional 24 percent of patients. Among the 8.9 percent of individuals in the primary prevention population who would be recommended for statins by ACC/AHA guidelines but not by USPSTF recommendations, 55 percent would be adults ages 40 to 59 years with an average 30-year cardiovascular risk greater than 30 percent, and 28 percent would have diabetes. "If these estimates are accurate and assuming these proportions can be projected to the U.S. population, there could be an estimated 17.1 million vs 26.4 million U.S. adults with a new recommendation for statin therapy, based on the USPSTF recommendations vs the ACC/AHA guideline recommendations, respectively--an estimated difference of 9.3 million individuals," the authors write. "Alternative approaches to augmenting risk-based cholesterol guidelines, including those that explicitly incorporate potential benefit of therapy, should be considered."Source: Eurekalert << 'World Liver Day' Creates Awareness to Prevent Liver Disease... Fast-Food Consumption Higher in Preschoolers Exposed to Tele... >> Recommended Reading USPSTF: Screening for Latent Tuberculosis Infection for High Risk Population Screening recommendation indicate that there is high certainty that the net benefit is moderate, or there is moderate certainty that the net benefit is moderate to substantial. READ MORE American Lung Association Hails the USPSTF’s New Tobacco Cessation Recommendation Harold P. Wimmer opines that the quitting smoking is one of the most effective things someone can do to improve their health and prevent illness and disease. READ MORE New Guidelines for the Treatment of Peripheral Artery Disease Recommendations on structured exercise programs and medical therapy are stated in the new guidelines for the treatment of peripheral artery disease. READ MORE Guidelines to Manage Dyslipidemia Released The new guidelines for the management of dyslipidemia highlights the need to lower lipid levels in populations and high risk individuals. READ MORE Cholesterol Cholesterol is produced by the body (liver) and is essential for normal body functioning. READ MORE Cholesterol - The Enigma Chemical The word 'Cholesterol' rings danger bells as soon as it is mentioned. This important chemical is important for the normal metabolism of the body and is dangerous only if present in excess. READ MORE Natural Remedies for Cholesterol – How Effective Are They? Certain natural remedies are effective in controlling high cholesterol, when aided by lifestyle changes. READ MORE Statins Statins are new wonder drugs that are proving to be efficacious, not merely in relieving symptoms but also offering several health benefits. READ MORE Most Popular on Medindia Nutam (400mg) (Piracetam) Turmeric Powder - Health Benefits, Uses & Side Effects Post-Nasal Drip More News on: CholesterolCholesterol - The Enigma ChemicalStatinsNatural Remedies for Cholesterol – How Effective Are They?