Researchers have discovered an unknown cellular pathway that can help physicians better understand end-stage liver disease. A team of researchers in the University of Arizona's College of Pharmacy has discovered a molecular pathway that could be key to creating new therapeutics that would slow or even reverse the progression of end-stage liver disease. According to the National Institutes of Health, cells keep oxidative stress under control through various mechanisms and most of these mechanisms involve Nrf2, a protein present in virtually every cell that acts as a molecular switch. The researchers said that Nrf2 activates various biochemical mechanisms inside the cell that capture reactive oxygen molecules or dispose of damaged cellular components before they can cause more trouble. The antioxidants found in many fruits and vegetables exert their healthful benefits by capturing reactive oxygen molecules. The study was published in the journal Genes and Development.Source: ANI << Rich Mother in China Rents 'Mountain' to Teach Daughter Abo... John Paul II and John XXIII Declared Saint by Pope Francis >> Recommended Reading Alcoholic Liver Disease Encyclopedia section of medindia gives general information about Alcoholic Liver Disease. READ MORE Treatment for Immune Suppression in Liver Disease Uncovered by Mechanism The susceptibility of liver disease patients to life threatening infections has been uncovered through a mechanism by a team of medical scientists who have also suggested a possible treatment. READ MORE Critical End-Stage Liver Disease Discovery Made by Scientists at the UA A molecular pathway that could be key to creating new therapeutics that can reverse the progression of end-stage liver disease has been discovered. READ MORE Research Links Gut Bacteria to Alcoholic Liver Disease Gut bacteria play an important role in determining the severity of alcoholic liver disease in heavy drinkers. READ MORE Biliary Cirrhosis Biliary cirrhosis occurs due to obstruction to the flow of bile through bile ducts either within the liver or outside the liver. READ MORE Current Treatments for Liver Cancer Current Treatments for Liver Cancer (also known as hepatoma or hepatocellular carcinoma) can result in complete cure of the disease if it is detected early. READ MORE Fatty Liver Disease: A Growing Health Problem in India Non alcoholic fatty liver disease (NAFLD) is the leading cause of liver dysfunction worldwide and is a rapidly growing health problem in India. READ MORE Hepatitis A Hepatitis A is the most benign of the hepatitis viruses and usually has no long term side effects. Hepatitis A vaccine is available that is 95% effective in preventing the disease. READ MORE Living Donor Liver Transplant: What Are the Risks? The risk of dying as a result of a living donor liver segment removal is between 0.2-2.0%. The risk of morbidity is anywhere between 1.3% (in highly experienced centers) to 60%. READ MORE Milk Thistle Milk Thistle is a resourceful natural plant which has many medicinal benefits. In herbal medication milk thistle is used in cases of liver diseases. READ MORE Wilson's Disease This is a rare inherited systemic disorder of copper metabolism, affecting the liver mainly before other organs. READ MORE Most Popular on Medindia How to Reduce School Bag Weight - Simple Tips Calculate Ideal Weight for Infants A-Z Drug Brands in India More News on: Alcoholic Liver DiseaseLiver BiopsyHepatitis ALiverWilson's DiseaseBiliary CirrhosisMilk ThistleCurrent Treatments for Liver CancerFatty Liver Disease: A Growing Health Problem in IndiaLiving Donor Liver Transplant: What Are the Risks?