A team of scientists is hoping to discover drugs for treating obesity. Scientists have found that there are many other factors contributing to eating habits, apart from leptin and ghrelin.
Jyoti Madhusoodanan, contributing editor, reported that early attempts to therapeutically target leptin and ghrelin, which suppress and stimulate appetite, respectively, were mostly ineffective. But the hormones' discoveries paved the way to a deeper understanding of the chemistry of hunger.
Focus Shifts to Target for Obesity Drugs
The way in which the hormone leptin interacts with a key receptor in the brain has been determined by researchers at the University of Michigan.
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‘A few more years of in-depth study for a deeper understanding of the chemistry of hunger is needed to treat obesity.’
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Scientists have found that in addition to leptin and ghrelin, many other factors contribute to eating habits. Protein sensors in the stomach, for example, sense stretch, pressure and volume changes when a person eats, and create a sense of fullness.
Neurotransmitters in the brain, including dopamine, serotonin and norepinephrine, also tweak people's feelings of hunger and satiety. Recognizing the role of the brain in weight gain, researchers developed newer therapies, approved in 2013 and 2014, to target individual neuronal signaling molecules.
![Obesity Drugs may Replace Gastric Bypass Surgery]( "Obesity Drugs may Replace Gastric Bypass Surgery")
A new drug treatment which pay prove to be a great alternative to gastric bypass surgery, is currently being developed by scientists
But to further improve obesity treatments, drugs will most likely need a more complex approach, given the multiple factors involved in hunger. So researchers are now trying combination therapies to better regulate various parts of the body's appetite control system.
A few more years of research could ultimately bear out this strategy or help redirect the field yet again. The study appears in Chemical & Engineering News (C&EN).
Source: ANI
Obesity Drugs may Replace Gastric Bypass Surgery
A new drug treatment which pay prove to be a great alternative to gastric bypass surgery, is currently being developed by scientists
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But to further improve obesity treatments, drugs will most likely need a more complex approach, given the multiple factors involved in hunger. So researchers are now trying combination therapies to better regulate various parts of the body's appetite control system.
A few more years of research could ultimately bear out this strategy or help redirect the field yet again. The study appears in Chemical & Engineering News (C&EN).
Source: ANI
Study Indicates That Physicians Prescribe More Diabetic Medications Than Obesity Drugs
Obesity is a major risk factor for diabetes, physicians prescribe 15 times more diabetic treatment medications than obesity drugs.
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 New Approaches for Evaluating Benefits and Risks of Obesity Drugs Outlined By George Washington University Consensus ReportA report was released today by the George Washington University School of Public Health and Health Services (GW). | Advertisement
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