About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Findings from Kentucky Breast Cancer Patients With Disease Relapse presented

by Kathy Jones on December 26, 2011 at 8:25 PM
Font : A-A+

Findings from Kentucky Breast Cancer Patients With Disease Relapse presented

Findings from studies on relapse of breast cancer were presented by the University of Kentucky Markey Cancer Center breast oncologist Dr. Suleiman Massarweh and his research team at the San Antonio Breast Cancer Symposium this month.

The two studies aimed to characterize further risk factors for presentation with metastatic disease or risk of early metastatic relapse after initial therapy. Data for each study was collected from 1,089 patients at the UK Markey Cancer Center between January 2007 and May 2011.

Advertisement

The studies showed that patients who present with metastatic disease in an initial diagnosis tend to be older, have lower grade tumors, a high frequency of estrogen receptor positive disease, and a predilection for bone metastasis. In contrast, patients who present with metastasis and early relapse after treatment tend to be younger and have more aggressive "triple negative" higher grade cancer that recurs despite appropriate therapy.

The findings suggest that initial presentation with metastatic disease is reflective of neglected breast cancer that is otherwise indolent, but patients chose to ignore it until they have no choice but to seek help. As a result, treatment then becomes more complex, more expensive and lifelong, with a major impact on quality of life and societal function.
Advertisement

Massarweh describes the neglect of metastatic disease as a social problem, an education issue and a matter of perception. Most women know they should get regular mammograms, he says, but widespread information on other facets of breast care — like self-exams, symptoms, and second opinions — are needed.

"The fear of a cancer diagnosis may drive patients to hide it from others, perhaps because they are more worried about the side effects of treatment and its impact on their lives," Massarweh said. "It's a shame that breast cancer, which is very otherwise treatable, ends up becoming incurable because of lack of awareness."

The kind of breast cancer that relapses early after therapy, within 2-3 years, reflects an aggressive resistant disease, despite appropriate therapy. In breast cancer with early relapse, Massarweh suggests that researchers should continue to test new therapeutic strategies to improve outcome.

"We clearly need to do more work and test novel therapy approaches to improve disease outcome, but also put major emphasis on increasing awareness about the importance of early detection and presentation when breast symptoms arise," Massarweh said. "In addition, it is very important that major cancer centers such as ours study their cancer populations more closely to identify characteristics of disease and guide the future of research and improving outcomes of patients."



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
H1N1 Influenza Prevention in Children: What Parents Need to Know
Dietary Factors Responsible for Dihydrotestosterone (DHT) Production and Hair Loss
Test Your Knowledge About Chromosomes?
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Women and Cancer Breast Biopsy Pagets disease of the breast Mastitis Cancer and Homeopathy Breast Cancer Facts Cancer Facts Cancer Tattoos A Body Art Breasts - Structures and Types 

Most Popular on Medindia

Sinopril (2mg) (Lacidipine) Nutam (400mg) (Piracetam) Daily Calorie Requirements Color Blindness Calculator Blood - Sugar Chart Indian Medical Journals Drug - Food Interactions Find a Doctor Hearing Loss Calculator Noscaphene (Noscapine)
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Findings from Kentucky Breast Cancer Patients With Disease Relapse presented Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests