
Scientists at UCLA have developed a new technique for creating
patient specific combination drug regimens that, at least in laboratory tests,
have shown more effective than existing techniques.
Moreover, to make the drug therapy even more powerful, the research
team used nanodiamonds in helping to deliver drugs to neoplastic cells.
Advertisement
The so-called Feedback System Control.II uses phenotypic information in evaluating the effectiveness of a particular drug combination. Once the optimal combo therapy has been identified, the drugs are assembled along with nanodiamonds attached to their surface.
The compounds were introduced to cancer cell lines and the
nanodiamonds acted as anchors that prevented the drugs from being excreted by
the cancer cells. This allowed the drug therapy to act for longer periods of
time, getting the most out of each drug payload without harming as many healthy
cells nearby.
Combination therapy, particularly in cancer treatment, is a common way of attacking aggressive diseases, but they often miss their targets.
"This optimized nanodrug combination approach can be used for virtually every type of disease model and is certainly not limited to cancer. Additionally, this study shows that we can design optimized combinations for virtually every type of drug and any type of nanotherapy," said Dr. Chih-Ming Ho, a professor of mechanical engineering at UCLA.
Source: Medindia
Advertisement
Combination therapy, particularly in cancer treatment, is a common way of attacking aggressive diseases, but they often miss their targets.
"This optimized nanodrug combination approach can be used for virtually every type of disease model and is certainly not limited to cancer. Additionally, this study shows that we can design optimized combinations for virtually every type of drug and any type of nanotherapy," said Dr. Chih-Ming Ho, a professor of mechanical engineering at UCLA.
Source: Medindia
Advertisement
Advertisement
|
Advertisement
Recommended Reading
Latest Cancer News

Chronotherapy (the sleep-wake cycle) is observed as a valuable alternative treatment in cancer diagnosis and treatment.

A nanoengineering platform targets neutrophils, the white blood cells without killing pancreatic cancer cells paving the way for effective treatments.

The survival rates between lobectomy and wedge resection surgical procedures were found to be the same among lung cancer patients.

The mechanism by which the kinases cause inflammation has been discovered by scientists.

Pancreatic cancer cases are on the rise. The biomarker approach could reduce the chance of developing pancreatic cancer.