Treatment can Benefit Patients With Both Thalassaemia and HCV

Due to contaminated transfusions before 1990,many individuals with the blood disorder thalassaemia also carry the hepatitis C virus (HCV).

A new study indicates that treatment with a combination of sofosbuvir and ledipasvir as a once a day single pill leads to a sustained virological response in 98% of patients with thalassaemia and HCV.

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Hepatitis C is an inflammation of the liver caused by a virus. It is primarily spread through blood and blood products, infected needles and from a pregnant mother to baby.

"The findings are significant because, unlike other antiviral drugs, this simple treatment is expected not to be limited by drug-to-drug interactions with other medications usually taken by thalassaemia patients," said Dr. Alessandra Mangia, lead author of the Alimentary Pharmacology & Therapeutics study.

Source-Eurekalert

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Due to the co-existence of iron overload (from repeated blood transfusions), these patients are at increased risk of developing liver cancer.

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Treatment can Benefit Patients With Both Thalassaemia and HCV

Due to contaminated transfusions before 1990,many individuals with the blood disorder thalassaemia also carry the hepatitis C virus (HCV).

TOP INSIGHT