About Careers MedBlog Contact us

Traumatic Brain Injury may be Treated by Drug Combo

by Kathy Jones on September 20, 2010 at 7:50 PM
Font : A-A+

 Traumatic Brain Injury may be Treated by Drug Combo

Drugs in combined doses that could help treat traumatic brain injury have been discovered by researchers at SUNY Downstate Medical Centre.

While the majority of TBIs are concussions or other mild forms, traumatic brain injuries contribute to a substantial number of deaths and cases of permanent disability and currently, there are no drugs available to treat TBI. A variety of single drugs have failed clinical trials, suggesting a possible role for drug combinations.


Peter J. Bergold and his colleagues tested five drugs in various combinations. Their observations suggest a potentially valuable role for minocycline plus N-acetylcysteine to treat TBI.

"There is great need for drugs to treat TBI. Perhaps the fastest way to get treatments to the clinic is to combine drugs already known to be both safe and effective. The combination of minocycline and N-acetylcysteine showed a large, synergistic improvement of cognition and memory after experimental traumatic brain injury. We are continuing these studies to get this combination in a clinical trial," Bergold said.

The results are published in the journal PloS One.

Source: ANI

Recommended Reading

This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

Traumatic Brain Injury may be Treated by Drug Combo Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests