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Traditional Chinese Exercise Boosts the Efficacy of Flu Vaccine

by VR Sreeraman on August 14, 2007 at 8:01 PM
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Traditional Chinese Exercise Boosts the Efficacy of Flu Vaccine

A new study has found that traditional Chinese exercises may increase efficacy of flu vaccine in older adults.

A team of kinesiologists at the University of Illinois suggest that older adults who adopt an exercise regimen combining Taiji and Qigong may get an extra boost from their annual flu shot.

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Qigong (chee-kung) and Taiji (tye-chee) - or Tai Chi, as it is more commonly known in the U.S. - combine simple, graceful movements and meditation. Qigong, which dates to the middle of the first millennium B.C., is a series of integrated exercises believed to have positive, relaxing effects on a person's mind, body and spirit. Taiji is a holistic form of exercise, and a type of Qigong that melds Chinese philosophy with martial and healing arts.

"We have found that 20 weeks of Taiji can increase the antibody response to influenza vaccine in older adults," said the study's lead author Yang Yang.
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"In this study, we found that five months of an easily performed behavioural Taiji and Qigong intervention could improve the magnitude and duration of the HI anti-influenza antibody titer response in a small cohort of older adults," write the authors.

According to the researchers, one problem with the flu vaccine is that older adults often do not reach what are considered to be "protective levels" after receiving the vaccination.

For the current study, 41 subjects were recruited from the larger data pool. Twenty-seven had received the Taiji/Qigong intervention; 14 were from the study's wait-list control group, and another 9 individuals who did not participate in the exercises were added to balance the size of the control group.

Sub-study participants provided detailed medical histories, received sleep-quality evaluations and submitted blood samples for analysis before injection with the influenza vaccine. Blood also was drawn 3, 6 and 20 weeks following vaccination, and samples were sent to a Center for Disease Control-affiliated reference laboratory in New Jersey for blinded analysis of anti-influenza antibody titer by hemagglutination inhibition assay.

Titer, according to Yang, refers to "a measurement of the amount of antibodies in the blood."

Those in the exercise intervention group participated in three one-hour classes for 20 weeks, while the control group was directed to continue their regular activities for the same time period. Each class consisted of equal parts Qigong and Taiji, which included movements emphasizing mobility skills such as weight shifting, range of motion and coordination, and sitting and standing meditation.

The boffins found that on an average, the Taiji group had much higher antibody responses to the vaccination than the control group, and the percentage of persons who achieved protective levels also was higher in the Taiji group.

"Our results provide 'proof-of-concept' and suggest that there needs to be a larger dedicated intervention trial with Taiji to definitively determine whether this type of behavioral intervention can improve influenza vaccine efficacy in older adults," said Yang.

Yang, who will discuss the work as a featured speaker at a Sept. 21 clinical conference hosted by Mayo Clinic in Rochester, Minn., said this is the first study to examine the effects of traditional Taiji intervention on the response to influenza vaccine in older adults.

While the Chinese have long believed the exercises result in a range of physical, mental and spiritual benefits for practitioners, until recently, evidence has been largely anecdotal. Yang's overarching research focus is to use Western scientific practices to validate centuries of anecdotal claims and reveal what he calls "the essence of the tradition."

"We want to demystify it and make the average person go straight to the core of the secret. Our overall goal is to let the essence of this tradition reach the general public," he said.

"The use of Taiji as a behavioral intervention in older adults is particularly attractive due to age-related loss of function and problems with even moderate intensity exercise interventions," the authors note in their report.

The study is scheduled for publication in the August issue of the American Journal of Chinese Medicine.

Source: ANI
LIN/J
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