About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Type of Fat You Consume Determines Differentiation of Your Stem Cells

by Anjali Aryamvally on December 3, 2017 at 1:00 PM
Type of Fat You Consume Determines Differentiation of Your Stem Cells

You are what you eat when it comes to fat, reports a research team from McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth) in the journal Science Advances.

Dietary fats are converted into lipids, which make up the membranes that surround all living cells. The type of fat a person consumes may determine whether stem cells are converted into bone cells or fat cells, said Ilya Levental, Ph.D., the study's senior author and assistant professor of integrative biology and pharmacology at McGovern Medical School at UTHealth.

Advertisement


"The fats that we consume such as cholesterol, unsaturated fats and fish oil become robustly incorporated into the membranes of our cells and dramatically change the composition and function of those membranes," said Levental, a Cancer Prevention & Research Institute of Texas (CPRIT) Scholar. To test their theory, Kandice Levental, Ph.D., the study's lead author and assistant professor of integrative biology and pharmacology at McGovern Medical School, measured the lipid content of mesenchymal (connective tissue) stem cells as they transformed into bone cells or fat cells.

The Leventals found that bone cell membranes had unique compositions, being particularly high in a type of dietary fat, omega-3 polyunsaturated fat. This fat is also called DHA and is the most abundant component of fish oil, a common dietary supplement. Most importantly, they found that adding such fish oil fats to mesenchymal stem cells pushed them to transform into osteoblasts (bone-forming cells) as opposed to adipocytes (fat-storing cells).
Advertisement

This fundamental research helps explain why fish oil might benefit people with osteoporosis, a bone weakening disorder. More broadly, it may provide insight into the many connections between dietary fats and a variety of clinical outcomes, including healthy aging and heart disease.

"Our investigations suggest a general mechanism by which dietary fats affect cellular physiology through remodeling of membrane lipidomes, biophysical properties and signaling," the authors wrote.



Source: Eurekalert
Font : A-A+

Advertisement

Advertisement
Advertisement

Recommended Readings

Latest Diet & Nutrition News

Unhealthy Snacking May Raise Risk of Metabolic Diseases
By replacing healthy meals with unhealthy snacks, one-fourth of people counteract the benefits of wholesome meals, increasing their risk of metabolic disorders.
Secret Behind America's Junk Food Obsession
Recent study underscores that food items from tobacco-affiliated companies exhibit a higher level of "hyperpalatability" compared to their rivals.
Keto Diet: A Recipe for PCOS Women to Boost Their Fertility
The Keto diet may improve reproductive health in PCOS women, reducing testosterone levels & aiding weight loss.
Lifelong Influence of Early Diet on Healthy Aging
A new study conducted in yeast underscores that maintaining a healthy diet during early life can significantly contribute to overall well-being during the aging process.
Disease-Causing Bacteria Found in Sanitized Ready-To-Eat Salad
A study offering a comprehensive review of research concerning minimally processed vegetables (MPVs), particularly centered on the Brazilian market.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
MediBotMediBot
Greetings! How can I assist you?MediBot
×

Type of Fat You Consume Determines Differentiation of Your Stem Cells Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests