About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Temperature Affects Insecticide Efficacy Against Malaria Vectors: Study

by Colleen Fleiss on April 15, 2018 at 11:40 AM
Font : A-A+

Temperature Affects Insecticide Efficacy Against Malaria Vectors: Study

Ambient temperature has an effect on the toxicity of the most commonly used insecticides for malaria control, revealed study led by ISGlobal, an institution supported by the "la Caixa" Foundation. The results, published in Malaria Journal, underline the need to evaluate the efficacy of these chemicals under real field conditions.

The appearance and spread of mosquitoes resistant to the insecticides currently used for malaria control is a threat to malaria elimination efforts. In Africa, resistance to pyrethroids (the only insecticide class approved for treating bed nets and used widely for indoor spraying) has been reported. It is therefore crucial to continuously monitor insecticide susceptibility - or resistance - among the main species of malaria-transmitting Anopheles. Insecticide efficacy is not only determined by the active ingredient, but also by other factors including ambient temperature. However, susceptibility tests are normally performed in laboratories or insectaries where temperature conditions are optimal for the mosquito.

Advertisement


In this study, the researchers explored the effect of temperature on the standard insecticide resistance test, using resistant or susceptible strains of two major malaria vectors (An. arabiensis and An. funestus). Toxicity of the pyrethroid deltamethrin and the carbamate bendiocarb was assessed at different temperatures (18, 25 or 30š).

Results show that temperature impacts toxicity of both insecticides, but in a different way: bendiocarb lost efficacy at higher temperatures for both species, regardless if they were resistant or susceptible. In contrast, higher temperatures decreased deltamethrin toxicity for susceptible arabiensis but the contrary was observed for resistant An. arabiensis and susceptible An. funestus. Piperonyl-butoxide (PBO), which inhibits pyrethroid-resistance mechanisms, completely restored deltamethrin susceptibility at all temperatures.
Advertisement

The authors conclude that caution must be exercised when drawing conclusions about a chemical's efficacy from laboratory assays performed at only one temperature. Temperatures in the field, they point out, can vary considerable during a single day.

"Performing efficacy tests with local vectors and under real field conditions (which would reflect the appropriate season and relevant time of day when chemicals are expected to act) would yield more accurate 'entomological intelligence' for evidence-based decision-making", says ISGlobal researcher Krijn Paaijmans, who coordinated the study.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
January is the Thyroid Awareness Month in 2022
Menstrual Disorders
Coffee May Help You Fight Endometrial Cancer
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Malaria-water Malaria Mosquito Diseases Organophosphorus Poisoning Fever Malaria - Protection Strategies 

Recommended Reading
Malaria
Malaria is caused by a parasite that enters blood through the bite of an infected mosquito. It is .....
Quiz on Malaria
Malaria is a common parasitic disease of the tropics, resulting in a million deaths every year. ......
New Mosquito Net can Protect Children from Malaria
A novel mosquito net treated with piperonyl butoxide, a chemical that blocks the mosquito's natural ...
Mefloquine May Be Effective in Preventing Malaria in Pregnant Women
Pregnant women who live in malaria transmission areas are more prone to the disease particularly if ...
Fever
Fever or Pyrexia is an elevation in normal body temperature. Causes of fever include infections, inj...
Malaria - Protection Strategies
Malaria is a dangerous disease with lethal consequences that requires protective measures for preven...
Mosquito Diseases
Mosquito-borne diseases, like malaria, filaria, dengue, etc are common in places conducive of mosqu...
Organophosphorus Poisoning
Organosphosphorus compounds are used as insecticides and chemical warfare. They are easily accessibl...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
ASK A DOCTOR ONLINE
I have read and I do accept terms of use - Telemedicine

Advantage Medindia: FREE subscription for 'Personalised Health & Wellness website with consultation' (Value Rs.300/-)