Misfolded amyloid beta proteins build up around the neurons as a plaque, interfering with them and eventually killing them. But this mechanism is not the only culprit. A recent study has identified that tau protein is a much more crucial component of Alzheimer's.
Tau protein normally assists in the transport of materials within neurons and similar to amyloid beta, misfolded tau builds up and spreads throughout the brain leading to neuron death.
The study is a huge leap in Alzheimer's research but scientists recommend amyloid beta be part of Alzheimer's diagnostics and research till there is adequate evidence regarding tau protein.