Medindia LOGIN REGISTER
Medindia
Advertisement

Targeted Vaccination Helps Halt Epidemics

by Colleen Fleiss on February 25, 2018 at 11:17 PM
Targeted Vaccination Helps Halt Epidemics

Vaccinations/immunizations remain the best way forward when it comes to stopping the spread of infectious diseases, reveal scientists from the Italian National Research Council and the JRC.

It's an option that is nearly always more effective than either doing nothing or attempting to contain an outbreak through quarantine.

Advertisement


This study looked specifically at epidemic outbreaks. They found that in such cases targeting carefully selected individuals with vaccination can be successful in containing the outbreak, even with only a relatively small number of individuals getting the relevant shot. v The scientists ran physics-based simulations on networks which sought to replicate the way individuals interact with one another in the real world, such as through the global air transportation network. The simulations are simplified versions of computational frameworks commonly used to investigate the global spread of real-world epidemics, such as Severe Acute Respiratory Syndrome (SARS). Nevertheless, they help understanding basic features of the more complicated and realistic models.

In the simulations, individuals correspond to 'nodes' that can transmit an infection through the links between them. The scientists found that quarantining nodes after the outbreak of an epidemic very quickly becomes ineffective. Quite early on in a simulated outbreak, even the 'do nothing' (non-intervention) strategy becomes preferable to quarantine.
Advertisement

Targeted vaccination was found to be the best option in nearly all epidemic cases. The scientists used a vaccination strategy based on 'optimal percolation', which consists of finding the least set of nodes that, when removed from a network, can fragment it into small clusters. The idea behind this approach is that fragmenting the network ensures infections are contained within small groups, hence preventing the occurrence of large outbreaks.

This might all seem like common sense, but preventive vaccination is not common practice for all illnesses and for some, vaccines do not yet exist. The norovirus outbreak at this year's Winter Olympic Games is an example where quarantine has been used as the option available to health officials. Medical professionals have attempted to initially contain the outbreak by imposing quarantine on the hundreds of staff who were unlucky enough to catch the virus. Despite these measures, the illness is continuing to spread and has started to affect some of the athletes.

In recent years, physicists have made significant advances in the field of network immunisation, developing increasingly efficient techniques to immunise a network by the 'removal' (vaccination) of a few nodes. This knowledge can help to support health policy as policymakers look to ensure increased global security against epidemics.

Source: Eurekalert
Font : A-A+

Advertisement

Advertisement
Advertisement

Recommended Readings

Latest Research News

South Korea's 2050 Forecast: Negative Growth Amid Low Fertility
South Korea's total fertility rate, averaging the number of children a woman aged 15-49 has in her lifetime, dropped to 0.81.
New Immunotherapy for Psoriasis & Vitiligo
Scientists identified mechanisms governing immune cells, selectively removing troublemakers to reshape skin immunity. Benefits those with psoriasis, vitiligo.
2050 Forecast: 1.06 Billion Individuals to Face 'Other' Musculoskeletal Disorders
By 2050, an anticipated increase from 494 million cases in 2020 to 1.06 billion people with musculoskeletal disabilities is expected.
Gene Therapies Can Disrupt Gaucher Disease Drug Market
Experts consulted by GlobalData anticipate a significant overhaul in the Gaucher disease scenario because of forthcoming gene therapies in development.
NASH Cases Expected to Hit 26.55 Million in 7MM by 2032
Within the seven major markets, 12% to 20% of diagnosed prevalent NASH cases present severe liver damage (stage 4 liver fibrosis), denoting cirrhosis.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Targeted Vaccination Helps Halt Epidemics Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests