About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Suspect Hip Implants Fit in Countless Folks

by Nancy Needhima on February 29, 2012 at 11:36 PM
Font : A-A+

Suspect Hip Implants Fit in Countless Folks

Countless people are fit with replacement hips whose flawed design is possibly exposing them to toxic metal, states a probe by the BBC and the British Medical Journal (BMJ) unveiled on Tuesday.

The risk comes from "metal on metal" joints that grind against each other, with the risk of leaking cobalt and chromium into the body, it said.

Advertisement

It pointed the finger at DePuy Orthopaedics, a subsidiary of the US medical conglomerate Johnson & Johnson, saying that the firm continued to sell the hips even after it knew of the risk.

The risk of leakage from cobalt-chrome implants has been known since 1975, when doctors discovered that local tissue reacts to ions, or charged atoms, from these metals, the investigators said.
Advertisement

"The ions can also leach into the bloodstream spreading to the lymph nodes, spleen, liver and kidneys before being excreted in urine," the BMJ said.

Lab research has also linked cobalt to a heart condition called cardiomyopathy and identified chromium ions as a probable carcinogen, it said.

The BMJ and the BBC news programme Newsnight said they had seen a DePuy internal memo from 2005.

"In addition to inducing potential changes in immune function, there has been concern for some time that wear debris may be carcinogenic," the memo reportedly said.

Despite this, "DePuy's marketing of metal-on-metal hips continued unabated, with promotional material failing to reflect internal company concerns," the BMJ-BBC probe charged.

In 2010, DePuy withdrew its ASR hip prosthesis and promoted another design called Pinnacle as "an alternative for the majority of patients."

But Pinnacle too had metal-on-metal problems and the following year, British researchers warned the national health safety watchdog of failures with this model, the report said.

There was no immediate response from DePuy to the allegations.

The investigation heaped blame on US and European health regulators for failing to respond to concerns or even requiring monitoring of patients who had received hips capable of producing toxic debris.

"Despite the fact that these risks have been known and well documented for decades, patients have been kept in the dark about their participation in what has effectively been a large uncontrolled experiment," said BMJ investigations editor Deborah Cohen.

"This isn't the unlucky failure to spot the misdemeanours of one rogue company or the occasional unforeseen breakdown of a small number of devices. It is the inability to prevent a whole class of failing hip implant from being used in hundreds of thousands of people globally."

The controversy coincides with a scandal over faulty breast implants.

More than 400,000 women around the world are thought to have received implants made by a French firm, PIP, which shut in 2010 after it was found to have used substandard, industrial-grade silicone gel.

Source: AFP
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
World Heart Day in 2022- Use Heart for Every Heart
Anemia among Indian Women and Children Remains a Cause of Concern- National Family Health Survey-5
H1N1 Influenza Prevention in Children: What Parents Need to Know
View all
Recommended Reading
News Archive
Date
Category
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Epilepsy Waist to Hip Ratio 

Most Popular on Medindia

A-Z Drug Brands in India Color Blindness Calculator Drug Side Effects Calculator Noscaphene (Noscapine) Nutam (400mg) (Piracetam) Indian Medical Journals Selfie Addiction Calculator Sinopril (2mg) (Lacidipine) The Essence of Yoga Hearing Loss Calculator
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
CONSULT ONLINE WITH A DOCTOR

×

Suspect Hip Implants Fit in Countless Folks Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests