About Careers Internship MedBlog Contact us

'Supermice' That can Resist Cancer and Ageing Developed

by VR Sreeraman on November 17, 2008 at 12:37 PM
 'Supermice' That can Resist Cancer and Ageing Developed

In a breakthrough study, Spanish scientists have created a genetically modified 'supermice' that can resist cancer and which age almost half as fast as other mice.

The research team from Valencia University modified the genes of the mice to make them resistant to cancer and slow down aging by increasing the amount of a particular protein called telomerase.


The protein helps cells to regenerate, allowing them to stay younger for longer.

Previous studies had shown that attempts to increase the amount of the protein in mice made them more vulnerable to cancer.

In the new study, the researchers modified the genes of the mice in such away that made it resistant to the disease.

The resulting mice were found to have better muscle in old age, healthier skin tissue and fewer digestion problems.

The mice aged 40 per cent slower than those whose genes have not been modified.

"By simultaneously increasing the amounts of telomerase and the resistance to cancer we are able to delay ageing in mice and also to extend their life span by 40 per cent," the Telegraph quoted Maria A. Blasco, lead researcher from the Spanish National Cancer Research Centre (CNIO).

"These mice get to live for as long as the eldest mice in records of the same kind,

"If we were to parallel it to humans, then it would mean reaching 120 years of age and also to start ageing much later in life," she added.

Source: ANI
Font : A-A+



Recommended Readings

Latest Research News

Brain Circuits That Shape Bedtime Rituals in Mice
New study sheds light on the intrinsic, yet often overlooked, role of sleep preparation as a hardwired survival strategy.
NELL-1 Protein Aids to Reduce Bone Loss in Astronauts
Microgravity-induced bone loss in space, can be reduced by systemic delivery of NELL-1, a protein required for bone growth and its maintenance.
Connecting Genetic Variants to the Alzheimer's Puzzle
Researchers establish connections between Alzheimer's-linked genetic alterations and the functioning of brain cells.
Gene Therapy Sparks Spinal Cord Regeneration
Team at NeuroRestore introduces a groundbreaking gene therapy that has effectively promoted nerve regrowth and reconnection, post spinal cord injury.
Unlocking the Gut Microbiome's Influence on Bone Density
Scientists aim to pinpoint particular functional pathways affected by these bacteria that may have an impact on skeletal health.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
Greetings! How can I assist you?MediBot

'Supermice' That can Resist Cancer and Ageing Developed Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests