About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Substance Abuse may Affect the Outcome in Schizophrenic Patients

by Rishika Gupta on November 4, 2017 at 5:13 PM
Font : A-A+

 Substance Abuse may Affect the Outcome in Schizophrenic Patients

Substance and drug abuse, when combined with antipsychotic medications, may affect the outcomes of schizophrenic patients found a new study published in Current Drug Abuse Reviews journal.

Many schizophrenic patients, who are treated by second-generation antipsychotic drugs, do not adhere to the pharmacotherapy and consume substances such as nicotine and alcohol or drugs such as cannabis and amphetamines.

Advertisement


Nicotine activates dopaminergic neurons, and alcohol increases dopamine release. These substances and drugs can worsen psychotic symptoms. We aimed to show measures to reduce substance and drug abuse and to increase patients' adherence to the pharmacological treatment.

Consuming such substances and drugs and the non-adherence to the pharmacotherapy worsens the outcome of the disease.

On the one hand, the administration of long-acting injectable antipsychotic drugs increases the adherence to the pharmacotherapy. On the other hand, psychoeducation can enable to reduce substances and drugs abuse.

Cannabis has two compounds, namely tetrahydrocannabidiol (THC), which is psychotomimetic, and cannabidiol (CBD), which has antipsychotic properties. CBD can reduce psychotic symptoms. Vancreline, a nicotinergic cholinergic agonist, can enable to reduce smoking.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Contraceptive Pills in Polycystic Ovary Syndrome (PCOS) Curtail Type 2 Diabetes Risk
Mushroom May Help Cut Down the Odds of Developing Depression
How to Battle Boredom during COVID
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Drug Abuse Screening Test Substance Abuse Disorder 

Recommended Reading
Cannabis Use in Adolescence Could Trigger Schizophrenia
The use of cannabis in adolescence could be a trigger for schizophrenia, reveals study....
Second-Hand Exposure To Cannabis, Alcohol Linked To Schizophrenia
Maternal alcohol abuse diagnosed before the birth of the child was associated with a 5.6 times ......
Psychiatric Drugs Have Contrasting Cognitive Effects in Schizophrenia
Psychiatric drugs like benzodiazepine and antidepressant medications reveal contrasting results on ....
Nicotine Normalizes Cognitive Problems Associated With Schizophrenia
Nicotine normalizes genetically-induced impairments in brain activity associated with ......
Substance Abuse Disorder
Substance abuse disorder is a dependency on substances that are hazardous when consumed in large ......

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use