Substance and drug abuse, when combined with antipsychotic medications, may affect the outcomes of schizophrenic patients found a new study published in Current Drug Abuse Reviews journal.
Many schizophrenic patients, who are treated by second-generation antipsychotic drugs, do not adhere to the pharmacotherapy and consume substances such as nicotine and alcohol or drugs such as cannabis and amphetamines.
Cannabis Use in Adolescence Could Trigger Schizophrenia
The use of cannabis in adolescence could be a trigger for schizophrenia, reveals study.
Advertisement
‘Substance abuse when combined with antipsychotic medications could worsen the outcome of schizophrenia’
Tweet it Now
Nicotine activates dopaminergic neurons, and alcohol increases dopamine release. These substances and drugs can worsen psychotic symptoms. We aimed to show measures to reduce substance and drug abuse and to increase patients' adherence to the pharmacological treatment.
Consuming such substances and drugs and the non-adherence to the pharmacotherapy worsens the outcome of the disease.
On the one hand, the administration of long-acting injectable antipsychotic drugs increases the adherence to the pharmacotherapy. On the other hand, psychoeducation can enable to reduce substances and drugs abuse.
Cannabis has two compounds, namely tetrahydrocannabidiol (THC), which is psychotomimetic, and cannabidiol (CBD), which has antipsychotic properties. CBD can reduce psychotic symptoms. Vancreline, a nicotinergic cholinergic agonist, can enable to reduce smoking.
Source: Eurekalert
On the one hand, the administration of long-acting injectable antipsychotic drugs increases the adherence to the pharmacotherapy. On the other hand, psychoeducation can enable to reduce substances and drugs abuse.
Cannabis has two compounds, namely tetrahydrocannabidiol (THC), which is psychotomimetic, and cannabidiol (CBD), which has antipsychotic properties. CBD can reduce psychotic symptoms. Vancreline, a nicotinergic cholinergic agonist, can enable to reduce smoking.
Source: Eurekalert
Second-Hand Exposure To Cannabis, Alcohol Linked To Schizophrenia
Maternal alcohol abuse diagnosed before the birth of the child was associated with a 5.6 times increased risk of schizophrenia in the child.
Advertisement
 Psychiatric Drugs Have Contrasting Cognitive Effects in SchizophreniaPsychiatric drugs like benzodiazepine and antidepressant medications reveal contrasting results on cognitive functioning in schizophrenia. | Advertisement
|
Nicotine Normalizes Cognitive Problems Associated With Schizophrenia
Nicotine normalizes genetically-induced impairments in brain activity associated with schizophrenia.
Advertisement
Recommended Readings
Latest Alcohol & Drug Abuse News
The United States is currently witnessing its highest overall mortality rates in over a century, driven in part by the surge in drug overdose fatalities.
Deciphering genetic factors in brain responses to METH and COC enables personalized approaches to combat drug abuse.
Giving rats DORA-12 during oxycodone withdrawal reduced future drug-seeking behavior, showing promise for preventing opioid addiction and relapse in humans.
Rising to 9.6% in 2021, daily vaping among New Zealand's 14-year-old students underscores a concerning youth trend.
The research also revealed a 22 percent increase in cadmium levels among marijuana users.
