
Coffee drinkers have yet another reason to relish their favorite drink - it can protect against Alzheimer's disease, say researchers.
The research team from University of South Florida has revealed that five cups of coffee not only helps reverse the effects of the disease but can treat it too.
Advertisement
They showed that caffeine significantly decreased abnormal levels of the protein linked to Alzheimer's disease, both in the brains and in the blood of mice exhibiting symptoms of the disease.
"The new findings provide evidence that caffeine could be a viable 'treatment' for established Alzheimer's disease, and not simply a protective strategy," said lead author Dr Gary Arendash, a USF neuroscientist with the Florida ADRC.
"That's important because caffeine is a safe drug for most people, it easily enters the brain, and it appears to directly affect the disease process."
During the study, the researchers gave half the mice caffeine in their drinking water. The other half got plain water.
At the end of the two-month study, the caffeinated mice performed much better on memory tests and thinking skills.
Mice genetically induced to develop the disease also showed a 50 per cent reduction in levels of amyloid protein in their brains.
Their memories were as sharp as those of healthy older mice without dementia.
"These are some of the most promising Alzheimer's mouse experiments ever done, showing that caffeine rapidly reduces beta amyloid protein in the blood, an effect that is mirrored in the brain, and this reduction is linked to cognitive benefit," said Dr Huntington Potter, director of the Florida Alzheimer's Disease Research Centre in Tampa.
Neil Hunt, chief executive of the Alzheimer's Society, said: Previous research into caffeine and dementia has suggested that it could delay Alzheimer's disease and even protect against vascular dementia.
"This research in mice suggests coffee may actually reverse some element of memory impairment," Hunt added.
The study is published in the Journal of Alzheimer's Disease.
Source: ANI
SRM
Advertisement
"That's important because caffeine is a safe drug for most people, it easily enters the brain, and it appears to directly affect the disease process."
During the study, the researchers gave half the mice caffeine in their drinking water. The other half got plain water.
At the end of the two-month study, the caffeinated mice performed much better on memory tests and thinking skills.
Mice genetically induced to develop the disease also showed a 50 per cent reduction in levels of amyloid protein in their brains.
Their memories were as sharp as those of healthy older mice without dementia.
"These are some of the most promising Alzheimer's mouse experiments ever done, showing that caffeine rapidly reduces beta amyloid protein in the blood, an effect that is mirrored in the brain, and this reduction is linked to cognitive benefit," said Dr Huntington Potter, director of the Florida Alzheimer's Disease Research Centre in Tampa.
Neil Hunt, chief executive of the Alzheimer's Society, said: Previous research into caffeine and dementia has suggested that it could delay Alzheimer's disease and even protect against vascular dementia.
"This research in mice suggests coffee may actually reverse some element of memory impairment," Hunt added.
The study is published in the Journal of Alzheimer's Disease.
Source: ANI
SRM
Advertisement
Advertisement
|
Advertisement
Recommended Readings
Latest Research News

South Korea's total fertility rate, averaging the number of children a woman aged 15-49 has in her lifetime, dropped to 0.81.

Scientists identified mechanisms governing immune cells, selectively removing troublemakers to reshape skin immunity. Benefits those with psoriasis, vitiligo.

By 2050, an anticipated increase from 494 million cases in 2020 to 1.06 billion people with musculoskeletal disabilities is expected.

Experts consulted by GlobalData anticipate a significant overhaul in the Gaucher disease scenario because of forthcoming gene therapies in development.

Within the seven major markets, 12% to 20% of diagnosed prevalent NASH cases present severe liver damage (stage 4 liver fibrosis), denoting cirrhosis.