About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Study Sheds Light on Antagonizing Atherosclerosis

by Kathy Jones on July 6, 2010 at 10:12 PM
Font : A-A+

 Study Sheds Light on Antagonizing Atherosclerosis

A study to be published online on July 5th in the Journal of Experimental Medicine says that antibody-producing B cells promote atherosclerosis in mice.

These findings came as a surprise, as prior studies had suggested that B cells help protect against the disease.

Advertisement

An international team of researchers, led by Ziad Mallat of the Paris Cardiovascular Research Center and the Division of Cardiovascular Medicine at the University of Cambridge, found that getting rid of B cells protected against atherosclerosis in mice. The protective effect was attributed to the increased production of an immune protein called interleukin-17, which was previously shown to hamper atherosclerosis in mice. Additional work is needed to understand how interleukin-17 interferes with the development of atherosclerotic lesions.

These findings raise the possibility that B cell-depleting drugs, currently used to treat patients with inflammatory disorders like rheumatoid arthritis, may also reduce their risk of atherosclerosis.



Source: Eurekalert
Advertisement
Advertisement
Advertisement

Recommended Reading

This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Study Sheds Light on Antagonizing Atherosclerosis Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests