"Having good neighbours and feeling connected to others in the local community may help to curb an individual's heart attack risk," said a statement that accompanied a study published in the Journal of Epidemiology and Community Health.
Heart and blood vessel diseases are the number one cause of death globally, claiming some 15 million lives in 2010, according to the latest Global Burden of Disease study.
Research into neighbourhoods and health had in the past focused on negative impacts through factors like fast-food restaurant density, violence, noise, traffic, poor air quality, vandalism and drug use, said the study authors.
For the latest research, the University of Michigan team used data from 5,276 people over 50 with no history of heart problems, who were participants in an ongoing Health and Retirement Study in the United States.
They monitored the cardiovascular health of the group, aged 70 on average and mainly married women, for four years from 2006 -- during which 148 of the participants had a heart attack.
At the start of the project, the respondents were asked to award points out of seven to reflect the extent to which they felt part of their neighbourhood, could rely on their neighbours in a pinch, could trust their neighbours, and found their neighbours to be friendly.
When they crunched the numbers at the end of the study, the team found that for every point they had awarded out of seven, an individual had a reduced heart attack risk over the four-year study period.
People who gave a full score of seven out of seven had a 67 percent reduced heart attack risk compared to people who gave a score of one, study co-author Eric Kim told AFP, and described the difference as "significant".
This was "approximately comparable to the reduced heart attack risk of a smoker vs a non-smoker," he said.
"This is an observational study so no definitive conclusions can be drawn about cause and effect," the statement underlined.
Limitations of the study included that researchers did not have access to the trialists' family history of heart disease and stroke.
But they had ruled out other possibly confounding factors like age, socio-economic status, mental health and underlying ailments like diabetes.
The mechanism behind the association was not known, but the team pointed out that neighbourly cohesion could encourage physical activities like walking, which counter artery clogging and disease.
"If future research replicates these findings, more neighbourhood-level public health approaches that target neighbourhood social cohesion may be warranted," the team wrote.