Cocaine-dependent men and women might benefit from different treatment options, according to a study conducted by Yale School of Medicine researchers.
The study, expected to be published online Jan. 31 in the American Journal of Psychiatry, suggests men and women with cocaine dependence might benefit more from different treatment options."There are differences in treatment outcomes for people with addictions who experience stress-induced drug cravings and those whose cravings are induced by drug cues," said Marc Potenza, professor of psychiatry, child study, and neurobiology and first author of the study.
"It is important to understand the biologic mechanisms that underlie these cravings."The researchers conducted functional magnetic resonance imaging scans of 30 cocaine-dependent individuals and 36 control subjects who were recreational drinkers. While undergoing brain scans, researchers then presented subjects with personalized cues (situations or events) the participants had indicated were personally stressful and other cues involving cocaine or alcohol.