Use of dietary flaxseed supplementation has no effect on total cholesterol, low-density lipoprotein cholesterol levels or total caloric intake, say researchers.
The randomized clinical trial included 32 participants ages 8 to 18 years with low-density lipoprotein cholesterol levels ranging from 135 mg/dL to less than 193 mg/dL. Participants were randomly assigned to either the intervention group or control group. The intervention group ate 2 muffins and 1 slice of bread daily containing flaxseed (30 grams flaxseed total). The control group ate muffins and bread substituted with whole-wheat flour.
The change in total and low-density lipoprotein cholesterol levels failed to exclude a potential benefit of flaxseed supplementation based on a prespecified minimum clinically important reduction of 10 percent.
Editor's Note: This study was supported by a grant from the Labatt Family Innovation Fund. Please see the articles for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.