About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Study Finds How Asbestos Causes Cancer

by Kathy Jones on July 1, 2010 at 11:02 PM
Font : A-A+

 Study Finds How Asbestos Causes Cancer

The mystery of why asbestos causes cancer has now been solved.

Researchers led by Drs. Haining Yang and Michele Carbone at the University of Hawai'i Cancer Research Center, found that when asbestos kills cells, it does so by inducing a process called "programmed cell necrosis" that leads to the release of a molecule called high-mobility group box 1 protein (HMGB1).

Advertisement

HMGB1 starts a particular type of inflammatory reaction that causes the release of mutagens and factors that promote tumour growth.

The researchers also found that patients exposed to asbestos have elevated levels of HMGB1 in their serum.

Thus, they stated that it might be possible to target HMGB1 to prevent or treat mesothelioma and identify asbestos-exposed cohorts by simple HMGB1 serological testing.
Advertisement

In the study, the researchers proposed that by interfering with the inflammatory reaction caused by asbestos and HMGB1, it may be possible to decrease cancer incidence among cohorts exposed to asbestos and decrease the rate of tumour growth among those already affected by mesothelioma.

This research emphasizes the role of inflammation in causing different types of cancers and provides novel clinical tools to identify exposed individuals and prevent or decrease tumour growth.

The researchers question if it will be possible to prevent mesothelioma, like colon cancer, simply by taking aspirin or similar drugs that stop inflammation. They are about to test this hypothesis.

The study is published in the current issue of the Proceedings of the National Academy of Sciences, U.S.A.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Ways to Manage Stress during COVID-19 Pandemic
Can Adjusting Fatty Acid Intake Improve Mood in Bipolar Disorder Patients?
Insulin Resistance Doubles the Risk of Major Depressive Disorder
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Mesothelioma Cancer and Homeopathy Cancer Facts Asbestosis Cancer Tattoos A Body Art Pneumoconiosis 

Recommended Reading
Congenital Cystic Adenomatoid Malformation Of The Lung
Congenital disease of the lung in which multiple cysts (water bubbles) develop in the lung tissues, ...
Mesothelioma - Animation
Animation on mesothelioma - a form of lung cancer, that explains about the condition, its risk ......
Asbestosis
Asbestosis is a chronic inflammatory lung disease that occurs due to long term exposure to asbestos ...
Mesothelioma
Mesothelioma is a rare, aggressive and deadly cancer of the mesothelial tissue lining the internal o...
Pneumoconiosis
Pneumoconiosis is a group of lung diseases caused by inhaled dust particles. It causes inflammation ...
Tattoos A Body Art
Tattoos are a rage among college students who sport it for the ‘cool dude’ or ‘cool babe’ look...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use