A percutaneous mitral valve clip designed to stop mitral valve regurgitation demonstrated clinical benefit as measured by the degree of mitral regurgitation, according to a study presented at the 22nd annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium, sponsored by the Cardiovascular Research Foundation. Mitral valve regurgitation is one of the most common forms of heart disease.
The study was led by James Hermiller, MD, Director of Cardiovascular Intervention at the St. Vincent Heart Center of Indiana (Indianapolis, IN.)
Mitral Valve Regurgitation and Mitral Valve Replacement
Mitral valve replacement is replacing the diseased mitral valve with an artificial valve.
Advertisement
"Significant measures of clinical benefit are observed one year following successful therapy," said Dr. Hermiller.
The study, EVEREST II, is a prospective, multi-center, randomized controlled trial designed to compare the safety and effectiveness of the MitraClip System with mitral valve surgery in the treatment of mitral regurgitation (MR). Measures of 12-month clinical benefit, defined as improvements in left ventricular (LV) function and symptomatic improvement, were evaluated for the Device Group and Control Group, and have been previously reported. However, observed clinical benefit by 12 month MR grade has not been reported.
![An Active Heart - Animation]( "An Active Heart - Animation")
Significant improvement in LV function, NYHA Functional Class, and Quality of Life scores was observed for all device patients with ongoing success (MR≤2+ at 12 months). Patients with MR reduced to 1+, 1+ to 2+, or 2+ at 12 months demonstrated marked clinical benefit, with significant improvements noted from baseline to 12 months.
A detailed analysis of these data will be presented during The 'Best of the Best' TCT 2010 Abstracts Session at 3:16 PM on Friday, September 24 in the Main Arena at the Washington Convention Center.
Source: Eurekalert
Advertisement
Significant improvement in LV function, NYHA Functional Class, and Quality of Life scores was observed for all device patients with ongoing success (MR≤2+ at 12 months). Patients with MR reduced to 1+, 1+ to 2+, or 2+ at 12 months demonstrated marked clinical benefit, with significant improvements noted from baseline to 12 months.
A detailed analysis of these data will be presented during The 'Best of the Best' TCT 2010 Abstracts Session at 3:16 PM on Friday, September 24 in the Main Arena at the Washington Convention Center.
Source: Eurekalert
Mitral Valve Disease and Replacement - Animation
Slide and animation on 'Mitral Valve Disease and Replacement' describing the anatomy, function of the valve and its replacement with an artificial one.
Advertisement
 Test Your Knowledge on HeartIntroduction: The heart is a fist-sized organ that pumps blood throughout the body. It is the primary organ of the human circulatory system that helps in circulation of blood throughout the body. The heart is a muscular organ powered by electrical impulses and is made up of four main chambers or sections. The brain and nervous system directs the heart's functioning . Take part | Advertisement
|
Advertisement
Recommended Reading
Latest Clinical Trials News
A new way to quickly eliminate fungal infections in the mouth has been developed by researchers at Penn Dental and Penn Engineering, using magnetically guided nanorobots.
Researchers tested the effectiveness of virus-mediated gene therapy for genetic hearing loss in an aged mouse model with genetic changes related to deafness.
The outcomes of the first clinical trial demonstrate the safety and efficacy of the measles-rubella (MR) vaccination to adults and infants as young as 9 months.
Scientists devise a fully integrated autonomous wearable ultrasonic-system-on-patch to sense deep tissue vital signs wirelessly even when the patient is on the move.
Combination of chemotherapy drugs was found to show promising results in patients with pancreatic cancer.