About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Study Claims Popular Anti-cholesterol Drug Crestor Cuts Heart Disease Risk by 44 Percent

by Tanya Thomas on November 10, 2008 at 5:36 PM
Font : A-A+

Study Claims Popular Anti-cholesterol Drug Crestor Cuts Heart Disease Risk by 44 Percent

A new study has claimed that the world's most popular anti-cholesterol drug Crestor, could be of use in more ways than one. Among patients who currently don't face a high risk of getting a heart disease, Crestor could reduce their risk further by nearly 44 percent.

The results of the study named JUPITER were presented at an annual meeting of the American Heart Association in New Orleans and were published online by the New England Journal of Medicine.

Advertisement

The study of 17,802 men and women aged 50 and more demonstrated that 20 milligrams of Crestor taken daily significantly reduced the combined risk of myocardial infarction, stroke, arterial revascularization, hospitalization for unstable angina, or death from cardiovascular causes by 44 percent compared to placebo among men and women with elevated hsCRP but low to normal cholesterol levels.

CRP is a protein produced by the liver that plays an important role in inflammatory processes and serves as a biological marker to measure the risk of artery blockage.
Advertisement

The research also showed that for patients in the trial taking Crestor the combined risk of heart attack, stroke or death from heart disease was reduced by 47 percent, the risk of heart attack was cut by more than half, the risk of stroke by nearly half and total mortality was reduced by 20 percent.

"These results provide new information about Crestor's effects on CV risk," said Howard Hutchinson, chief medical officer for pharmaceutical company AstraZeneca, which markets Crestor.

"The JUPITER trial confirmed that Crestor dramatically reduces LDL-C cholesterol levels and has now demonstrated a nearly 50 percent reduction in the risk of heart attack and stroke in a population of patients who had elevated hsCRP but low to normal cholesterol levels," Hutchinson added. "As is appropriate, the medical community, regulators, and guideline committees will now carefully consider these data and any implications for treating patients."

The study showed that a daily dose of 20 milligrams of Crestor was well tolerated in nearly 9,000 patients during the course of the trial.

There was no difference between treatment groups for major adverse events, including cancer or myopathy, the report said.

But there was a small increase in physician reported diabetes consistent with data from other large placebo controlled statin trials.

Crestor has now received regulatory approval in over 95 countries. Nearly 15 million patients have been prescribed Crestor worldwide.

Source: AFP
TAN
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
International Day of Persons with Disabilities 2021 - Fighting for Rights in the Post-COVID Era
Effect of Blood Group Type on COVID-19 Risk and Severity
Woman with Rare Spinal Cord Defect from Birth Sues Doctor
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Drug Toxicity Cardiac Catheterization Heart Attack Air travel: To fly or not to fly Diet Lifestyle and Heart Disease Body Mass Index Signature Drug Toxicity Silent Killer Diseases Heart Healthy Heart 

Recommended Reading
Cholesterol
Cholesterol is produced by the body (liver) and is essential for normal body functioning....
Cholesterol - The Enigma Chemical
The word 'Cholesterol' rings danger bells as soon as it is mentioned. This important chemical is .....
Heart Attack - Animation
Animation of Heart Attack symptoms. Heart attack is caused due to ischemia of the heart muscles ......
Air travel: To fly or not to fly
Air travel is for everyone, even those with medical conditions....
Body Mass Index
Body mass index (BMI) is a simple tool that is generally used to estimate the total amount of body f...
Cardiac Catheterization
Cardiac catheterization is a radiological procedure for both diagnosis and treatment of heart condit...
Drug Toxicity
Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a d...
Heart Attack
Heart attack is the death of the heart muscle due to loss of blood supply. Heart disease is the lead...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use