About Careers MedBlog Contact us

Studies Show Migraine may Not be Associated With Breast Cancer

by Kalyani Thivakaran on December 13, 2014 at 4:10 PM
Font : A-A+

 Studies Show Migraine may Not be Associated With Breast Cancer

A new study published on December, 12 in the JNCI: Journal of the National Cancer Institute reports that migraine, which has been proposed to be associated with breast cancer risk or differences in the endogenous sex hormones, has been proven not to be associated with any of these.


Studies linking migraine to breast cancer have reported inconsistent results. Furthermore, a biological mechanism underlying such an association has not been investigated although some have proposed that endogenous hormone levels, including estrogen, may be responsible because higher hormone levels have been associated with breast cancer and fluctuating levels have been shown to trigger migraines. To investigate this further, Rulla M. Tamimi, Sc.D., from the Channing Division of Network Medicine at the Department of Medicine at Brigham and Women's Hospital at Harvard Medical School in Boston, MA, and colleagues, analyzed data from 115,378 women, 17,696 of whom who reported a physician's diagnosis of migraine and found migraine was not associated with breast cancer. Furthermore, among 2034 pre-menopausal women, endogenous sex hormone levels did not differ by migraine status. The authors next performed a meta-analysis of 5 studies (including their study) and found migraine was associated with a lower risk of breast cancer overall, but when they stratified by study design this relationship was limited to the pooled case-control studies but not the pooled prospective cohort studies. The difference in findings according to study designs, may reflect additional limitations that may occur in case-control studies that can be more easily avoided in prospective cohort studies.

The authors conclude, "In this large cohort study, migraine was not associated with breast cancer risk or differences in endogenous sex hormone levels."

Source: Eurekalert

Recommended Reading

This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

Studies Show Migraine may Not be Associated With Breast Cancer Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests