Intervening in production of dysfunctional cells could mitigate stroke-induced memory impairments, revealed research published in JNeurosci.
Mice produce new neurons in the hippocampus following a stroke that fail to develop properly, finds new research published in JNeurosci. Intervening in the production of these cells may help to mitigate stroke-induced memory impairments.
How to Deal with a Stroke
Stroke is a brain attack, which occurs when the blood supply to the brain is interrupted. It affects all age groups; according to the WHO, 15 million people are affected by stroke annually.
Advertisement
‘The new finding begins to uncover the cellular mechanisms underlying post-stroke neuropsychiatric disorders.’
Tweet it Now
Stroke has long been known to increase adult neurogenesis. Despite the proliferation of new cells in a brain region critical for memory, previous stroke research in animals shows this process is accompanied by deficits on tasks that depend on the hippocampus. These observations led Albrecht Kunze and colleagues to investigate how newborn cells mature and integrate into the existing hippocampal network after stroke.
By temporarily cutting off blood supply to the brains of male and female mice, the researchers demonstrate the neurons generated as a result of this stroke model develop into hyperexcitable cells that may contribute to hippocampal dysfunction.
Source: Eurekalert
Source: Eurekalert
Stroke
Stroke can cause permanent disability and it is important to recognize its early warning signs to stop its progress. Early warning signs of stroke include sudden weakness of facial muscles.
Advertisement
 Quiz on StrokeStroke is the third leading cause of death world over. Besides, it also disables the affected people, making them completely dependent on caregivers for their daily needs. Lifestyle greatly affects the chances of developing a stroke. Thus, the incidence of stroke can be brought down to a great extent by leading a healthy lifestyle. Here is a quiz that tests if you know enough about this disabling | Advertisement
|
Stroke Risk Calculator
Stroke Risk Calculator checks if you have hypertension, diabetes and heart failure and predicts the risk of stroke (cerebrovascular accident) in next 10 years.
Advertisement
Recommended Readings
Latest Research News
Consuming a diet rich in saturated fats triggers persistent, low-level inflammation within the body, ultimately contributing to the onset of metabolic syndrome.
Ae. aegypti mosquitoes are carriers of "arthropod-borne" or "arbo-" viruses, which encompass the dengue virus, yellow fever virus, Zika virus, and chikungunya virus.
Cerebrospinal fluid (CSF) leaks are detected in approximately 1-3% of adults who have experienced a traumatic brain injury.
The optogenetic activation of hippocampal astrocytes can be viewed as a novel therapeutic avenue for addressing Alzheimer's disease.
In Alzheimer's disease condition, the control and adjustment of ABCA7 levels in response to inflammation and the decrease in the availability of cholesterol.
