HSP10 (Heat Shock Protein), helps monitor and organise protein interactions in the body, and responds to environmental stresses, such as exercise and infection, by increasing its production inside cells. Researchers at Liverpool, in collaboration with colleagues at the University of California, found that excessive amounts of HSP10 inside mitochondria - 'organs' that act as energy generators in cells - can halt the body's ageing process by preserving muscle strength.
HSP10 occurs naturally in all living organisms and scientists believe that study into its functions could prove significant for the design of future health care for the elderly, who are particularly susceptible to muscle damage. Researchers examined the role HSP10 plays inside cells, to further understand how ageing muscle tissue can recover from stress.
Professor Anne McArdle, from the University's School of Clinical Sciences, said: "We studied the role of HSP10 inside mitochondria, as it is here that unstable chemicals are produced which can harm parts of the cell. The damage caused by this is thought to play an important part in the ageing process, in which skeletal muscle becomes smaller and weaker and more susceptible to stress damage.
"We now need to look at how we might artificially increase production of HSP10 in the body, specifically in relation to ageing muscle, to see if the protein could be used as a therapeutic measure. In time, clinical trials must take place to establish what benefits HSP10 can have on human quality of life, such as preservation of muscle strength."