Chemotherapy or radiation therapy leads to loss of stem cells that ends in anaemia, appetite and weight loss in cancer patients.

They've also known that a gene called Puma is critical for p53 to initiate the cell death of DNA-damaged cells, reports Nature.
"You can target Puma to prevent p53-mediated depletion of adult stem cells, because a Puma deficiency does not promote the development of cancer," said Yang Xu at UC San Diego.
"If you can suppress Puma function, you can rescue a lot of the adult stem cells that would otherwise be lost after the accumulation of DNA damage such as during cancer therapy," he added.
The team published its findings in this week's advance online issue of the journal Nature Cell Biology.
Source-ANI