About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Stem Cell Breakthrough Brings Prostate Cancer Treatment Closer to Reality

by Bidita Debnath on December 2, 2013 at 10:55 PM
Font : A-A+

 Stem Cell Breakthrough Brings Prostate Cancer Treatment Closer to Reality

Prostate cancer can develop in one type of stem cell, then evolve to be maintained by a stem cell that looks very different, making prostate cancer stem cells a "moving target" for treatments, find researchers.

The breakthrough discovery, by Drs. Andrew Goldstein, Owen Witte, and Tanya Stoyanova and their colleagues from UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, connects directly to the development of future therapeutics that target cancer.

Advertisement

Adult stem cells are tissue-specific regenerative cells that replace diseased or damaged cells in the body's organs.

Researchers found that tumours can start in basal stem cells that evolve to luminal-like cells. This means that the source of the disease they wish to target with therapy - the tumour stem cell - can change over time.
Advertisement

"People have begun to think about cancers as being driven by stem cells in the same way that many of our adult organs are maintained by dedicated stem cells," said Goldstein, "based on this new understanding, a lot of excitement surrounds the concept of going right to the root of the tumor and targeting those stem cells to eradicate the cancer."

In patients with aggressive prostate cancer who are being treated with anti-androgen therapy, the basal stem cells that start the cancer look different from the luminal cells that maintain the aggressive disease, and in turn the tumour stem cells that remain after the anti-androgen treatment look different from the previous two.

This means that for targeting treatments, researchers need to identify cell types that evolve as the disease and its treatment progress.

The study was published in the Proceedings of the National Academy of Sciences.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Breast Cancer Awareness Month 2021 - It's time to RISE
First-Ever Successful Pig-To-Human Kidney Transplantation
World Osteoporosis Day 2021 -
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Stem Cells - Cord Blood Prostate Cancer Stem Cells - Fundamentals Cancer and Homeopathy Parkinsons Disease Surgical Treatment Trans-Urethral Resection of the Prostate Genetics and Stem Cells Prostate Cancer Facts Cancer Facts Cancer 

Recommended Reading
Prostate Specific Antigen [PSA]
PSA blood test is specific to prostate gland but not necessarily a cancer specific test but is ......
Prostate Cancer Screening
PSA (Prostate Specific Antigen) test and Digital Rectal Examination are two tests that allow ......
Prostate Cancer: Treatment Options
Treatment options of prostate cancer includes waiting, surgery, radiation, hormone therapy, ......
Prostate Cancer
This cancer affects men over the age of 50 years and screening with rectal examination and PSA can h...
Stem Cells - Fundamentals
Encyclopedia section of medindia gives general info about Stem Cells...
Stem Cells - Cord Blood
Encyclopedia section of medindia gives general info about Cord Blood...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use