Medindia
Advertisement

Smell of Food Affects Life Expectancy by Controlling Cellular Recycling

by Mohamed Fathima S on February 21, 2019 at 1:31 PM
Font : A-A+

Smell of Food Affects Life Expectancy by Controlling Cellular Recycling

Food odors have demonstrated influence on proteostasis (balance between formation and degradation of proteins), finds a study carried out in the roundworm Caenorhabditis elegans, a key model organism in biomedical research. Also, the study showed that out of 358 neurons that comprise of the nematode nervous system, two of them are part of the olfactory system that is significant for odor perception.

The smell of food induces a variety of physiological processes in our body. Thus, the production of saliva and digestive enzymes is stimulated before the actual food intake in order to prepare the gastrointestinal tract for the upcoming digestive process. In a healthy organism, this coordination depends on a dynamic balance between formation and degradation of proteins (proteostasis). This plays an important role for the recycling of cells and during the aging process.

Advertisement


The researchers were able to uncover the influence of smelling on the physiology of the digestive tract by investigating the recycling of green fluorescent proteins in the intestine. The brighter the green fluorescent signal within the worms, the more severe the accumulation of cellular waste, strongly correlating with defective protein degradation.

The underlying processes are mediated by the regulatory microRNA molecule mir-71. This molecule regulates the genetic program of olfactory neurons and, afterwards, degradation processes in the digestive tract. However, if this mechanism is blocked, not only are cellular recycling processes diminished, the animal's lifespan is also reduced. In other words, roundworms with a non-functional 'sense of smell' live much shorter - a strong indication for its physiological significance.
Advertisement

This mechanism is central for the proper processing of odor signals and mediates adjustments in the intestinal cells. 'We assume that the organism coordinates food intake and effective degradation this way', commented first author Dr. Fabian Finger, who was recently awarded with the Klaus Liebrecht Prize of the UoC for his work.

'The impact of odors at the cellular level is a poorly investigated field', says Thorsten Hoppe. 'It is well known that malfunctions in odor perception are associated with neurodegenerative diseases. We will further investigate the influence of the perception of odors on aging-associated disorders such as Alzheimer's or Parkinson's disease.'



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Gonorrhea
World Alzheimer's Day 2021 - 'Know Dementia, Know Alzheimer's
'Hybrid Immunity' may Help Elude COVID-19 Pandemic
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Anosmia Why Do We Eat - Nutrition Facts Diet Lifestyle and Heart Disease Hunger Fullness and Weight Control Label Lingo on Food Items: Decoded Tips for Healthy Fasting During Ramadhan Top Diet Foods that Make you Fat Top Food for Dieters Selenium - Natural Source Better than Supplements Directing the Course to Healthy Aging 

Recommended Reading
Top 15 Dos and Don´ts for Preventing and Managing Dengue Fever
Dengue can be easily prevented and managed if you follow proper precautionary measures. Here we ......
Top 7 Most Essential Anti-Aging Ingredients That Work
Anti-aging ingredients can prevent signs of aging such as wrinkles, dryness, and sagging of skin. .....
Anti-aging Secrets to a Younger You
Is there anyone in this world who fails to be swayed by the magic of youth? None, for when youth ......
Anti-Aging Treatment with Vinotherapy or Wine Facials
Experience the bliss of vinotherapy - the power of grapes for a kissable skin....
Anosmia
Anosmia is the inability to perceive smell. Most patients with anosmia complain of losing the sense ...
Directing the Course to Healthy Aging
An understanding of the rise in the aging population over the years and the need for attention to im...
Hunger Fullness and Weight Control
An erratic way of eating or any metabolic disturbance in the hunger fullness signals is one of the m...
Label Lingo on Food Items: Decoded
Read on to become a “pro” in “label reading” and don’t get tricked by fancy promotions of food produ...
Selenium - Natural Source Better than Supplements
Selenium is a powerful anti-oxidant that prevents cell damage and helps in thyroid hormone productio...
Tips for Healthy Fasting During Ramadhan
Ramadhan calls for a change in your food habits, and to help you glide through it easily, here we’ve...
Top Diet Foods that Make you Fat
Every nutrition fad comes with its share of diet foods. While they seem healthy, many diet foods pro...
Top Food for Dieters
A diet food contains protein, fiber and good fats, which help in weight management. Diet foods if co...
Why Do We Eat - Nutrition Facts
The importance of eating food and the physiological, psychological and social functions of food....

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use