Medindia
Advertisement

Simple Blood Test can Determine the Preterm Birth Rate in Low-resource Countries

by Iswarya on March 20, 2019 at 12:23 PM

Simple Blood Test can Determine the Preterm Birth Rate in Low-resource Countries

New study finds that a simple blood test can predict preterm birth rate without ultrasound in low-resource countries. The findings of the study are published in the journal eLife.

Preterm birth is a leading cause of death among children under the age of five, with low resource countries facing the greatest challenge. But before solutions can be tested, researchers first need to be able to accurately measure the problem at a population level. This has been particularly difficult in countries where pregnant women don't have routine access to ultrasound technology to determine gestational age.

Advertisement


New research shows that a mathematical model developed in Canada could help. The model, developed with support from the Bill & Melinda Gates Foundation, relies on simple blood tests done soon after birth, as well as birth weight and sex.

"We're using metabolic fingerprints - unique patterns in specific molecules found in the blood - to help estimate gestational age," said senior author Dr. Kumanan Wilson, an internal medicine specialist and senior scientist at The Ottawa Hospital and professor at the University of Ottawa. "This could be crucial to global efforts to reduce preterm birth and improve newborn health."
Advertisement

Dr. Wilson developed the model together with Dr. Steven Hawken, a scientist, and big data expert at The Ottawa Hospital and assistant professor at the University of Ottawa. After validating the model using Canadian data, they teamed up with researchers from Bangladesh to try it in another setting.

The team enrolled more than 1,000 pregnant women in the study from Matlab, a research field station of the International Centre for Diarrhoeal Disease Research, Bangladesh. The women received regular ultrasounds as a gold standard reference for gestational age. Soon after birth, a few drops of newborn blood were collected from either a heel prick or the umbilical cord. The blood samples were sent to Newborn Screening Ontario in Ottawa, Canada for testing and the data was analyzed at The Ottawa Hospital.

With the heel prick blood samples, the mathematical model could accurately estimate gestational age to within two weeks of the ultrasound-validated age 94 percent of the time. Using the cord blood samples, the model was accurate to within two weeks 90 percent of the time.

The team is now partnering with Stanford University to implement their test in several other countries. They are also exploring the use of artificial intelligence to make it even better.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
'Hybrid Immunity' may Help Elude COVID-19 Pandemic
Stroop Effect
Plant-Based Diet may Reduce the Risk of COVID-19
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Thalassemia Undescended Testicles Varicocele Quiz on Depression Testicle Pain - Symptom Evaluation Blood in Stools - Symptom Evaluation Bombay Blood Group Torsion Testis Top 10 Alarming Risks of Low Birthweight in Babies Orchidectomy 

Recommended Reading
Extending Nephron Development In Preterm Babies May Prevent Kidney Disease Later
Scientists identify a possible therapeutic target to extend kidney development in preterm babies ......
Many Preterm Babies Still Exposed to Early Antibiotics
Antibiotics given to protect preterm babies come with potential risks. Unnecessary early antibiotic ...
Women With Bipolar Disorder at Greater Risk of Delivering Preterm Babies
Women who have been previously hospitalized for bipolar disorder are nearly twice as likely to have ...
Blood in Stools - Symptom Evaluation
Blood in stools results from bleeding that arises from any part of the digestive tract. Causes of bl...
Bombay Blood Group
Bombay blood group is a rare blood type in which the people have an H antigen deficiency. They can r...
Testicle Pain - Symptom Evaluation
A sudden, severe pain in the testis may be due to testicular torsion. Testicles inside the scrotum a...
Thalassemia
Thalassemia is an inherited blood disorder passed on through parental genes causing the body to prod...
Top 10 Alarming Risks of Low Birthweight in Babies
Low birthweight is a term given to babies who weigh less than 2,500 grams at birth. These babies loo...
Torsion Testis
Torsion occurs when the testis spins, twisting the spermatic cord, causing reduced blood flow and te...
Undescended Testicles
An undescended testicle / testis is one that has not descended into the scrotal sac before birth. It...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use