Research has shown that expression of soluble CD40L has been shown to increase significantly in conditions such as stroke, myocardial infarction, unstable angina, high cholesterol, or other cardiovascular events.
95% of the circulating CD40L exists in activated platelets. However, the specific pathway of the transition of CD40L is not elucidated, and whether Golgi apparatus is involved in the expression of platelet CD40L still needs to be proven. Dr. Wei Lu and colleagues from Second Xiangya Hospital, Central South University, found that platelet Golgi apparatus displayed significant morphological changes, which were possibly associated with enhanced synthetic and secretory functions of activated platelets after acute cerebral infarction. Golgi apparatus participated in the synthesis and transport of CD40L to the platelet surface, which may be a new target for the treatment of acute cerebral infarction. These findings were published in the Neural Regeneration Research (Vol. 8, No. 23, 2013).
Stroke
Stroke can cause permanent disability and it is important to recognize its early warning signs to stop its progress. Early warning signs of stroke include sudden weakness of facial muscles.
Source: Eurekalert
How to Deal with a Stroke
Stroke is a brain attack, which occurs when the blood supply to the brain is interrupted. It affects all age groups; according to the WHO, 15 million people are affected by stroke annually.
 Stress and the Gender DivideStress has become entwined in the current lifestyle of a young working couple and has resulted in the rise in incidence of hypertension, diabetes and psychosomatic illnesses. | Advertisement
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